Identification and Replication of a Combined Epigenetic and Genetic Biomarker Predicting Suicide and Suicidal Behaviors

Overview

Journal Am J Psychiatry

Specialty Psychiatry

Date 2014 Jul 31

PMID 25073599

Citations 67

Authors

Jerry Guintivano

Tori Brown

Alison Newcomer

Marcus Jones

Olivia Cox

Brion S Maher

William W Eaton

Jennifer L Payne

Holly C Wilcox

Zachary A Kaminsky

Affiliations

Soon will be listed here.

Abstract

Considerable research suggests that suicide involves effects of genes, the environment, and their interaction. Analysis of three independent data sets of post-mortem brains revealed signs of increased methylation in one particular gene, SKA2, a finding that was extended to peripheral blood samples from other cohorts of prospectively followed individuals.

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