» Articles » PMID: 25038553

OntoVIP: an Ontology for the Annotation of Object Models Used for Medical Image Simulation

Abstract

This paper describes the creation of a comprehensive conceptualization of object models used in medical image simulation, suitable for major imaging modalities and simulators. The goal is to create an application ontology that can be used to annotate the models in a repository integrated in the Virtual Imaging Platform (VIP), to facilitate their sharing and reuse. Annotations make the anatomical, physiological and pathophysiological content of the object models explicit. In such an interdisciplinary context we chose to rely on a common integration framework provided by a foundational ontology, that facilitates the consistent integration of the various modules extracted from several existing ontologies, i.e. FMA, PATO, MPATH, RadLex and ChEBI. Emphasis is put on methodology for achieving this extraction and integration. The most salient aspects of the ontology are presented, especially the organization in model layers, as well as its use to browse and query the model repository.

Citing Articles

An extensible and unifying approach to retrospective clinical data modeling: the BrainTeaser Ontology.

Faggioli G, Menotti L, Marchesin S, Chio A, Dagliati A, de Carvalho M J Biomed Semantics. 2024; 15(1):16.

PMID: 39210467 PMC: 11363415. DOI: 10.1186/s13326-024-00317-y.


Ontologies for Liver Diseases Representation: A Systematic Literature Review.

Messaoudi R, Mtibaa A, Vacavant A, Gargouri F, Jaziri F J Digit Imaging. 2019; 33(3):563-573.

PMID: 31848894 PMC: 7256132. DOI: 10.1007/s10278-019-00303-2.


Ontology-Based Approach for Liver Cancer Diagnosis and Treatment.

Messaoudi R, Jaziri F, Mtibaa A, Grand-Brochier M, Ali H, Amouri A J Digit Imaging. 2018; 32(1):116-130.

PMID: 30066122 PMC: 6382636. DOI: 10.1007/s10278-018-0115-6.


Biomedical imaging ontologies: A survey and proposal for future work.

Smith B, Arabandi S, Brochhausen M, Calhoun M, Ciccarese P, Doyle S J Pathol Inform. 2015; 6:37.

PMID: 26167381 PMC: 4485195. DOI: 10.4103/2153-3539.159214.

References
1.
Gkoutos G, Green E, Mallon A, Hancock J, Davidson D . Using ontologies to describe mouse phenotypes. Genome Biol. 2005; 6(1):R8. PMC: 549069. DOI: 10.1186/gb-2004-6-1-r8. View

2.
Aubert-Broche B, Evans A, Collins L . A new improved version of the realistic digital brain phantom. Neuroimage. 2006; 32(1):138-45. DOI: 10.1016/j.neuroimage.2006.03.052. View

3.
Langlotz C . RadLex: a new method for indexing online educational materials. Radiographics. 2006; 26(6):1595-7. DOI: 10.1148/rg.266065168. View

4.
Glatard T, Lartizien C, Gibaud B, da Silva R, Forestier G, Cervenansky F . A virtual imaging platform for multi-modality medical image simulation. IEEE Trans Med Imaging. 2012; 32(1):110-8. DOI: 10.1109/TMI.2012.2220154. View

5.
de Matos P, Alcantara R, Dekker A, Ennis M, Hastings J, Haug K . Chemical Entities of Biological Interest: an update. Nucleic Acids Res. 2009; 38(Database issue):D249-54. PMC: 2808869. DOI: 10.1093/nar/gkp886. View