Endoscopic Submucosal Dissection Vs Endoscopic Mucosal Resection for Colorectal Tumors: a Meta-analysis

Overview

Journal World J Gastroenterol

Publisher Baishideng Publishing Group

Specialty Gastroenterology

Date 2014 Jul 11

PMID 25009404

Citations 57

Authors

Jing Wang

Xiao-Hua Zhang

Jian Ge

Chong-Mei Yang

Ji-Yong Liu

Shu-Lei Zhao

Affiliations

Soon will be listed here.

Abstract

Aim: To compare the efficacy and safety of endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) for the treatment of colorectal tumors.

Methods: Databases, such as PubMed, EMBASE, Cochrane Library and Science Citation Index updated to 2013 were searched to include eligible articles. In the meta-analysis, the main outcome measurements were the en bloc resection rate, the histological resection rate and the local recurrence rate. Meanwhile, we also compared the operation time and the incidence of procedure-related complications.

Results: Six trials were identified and a total of 1642 lesions were included. The en bloc resection rate was higher and the local recurrence rate was lower in the ESD group compared with the EMR group (OR = 7.94; 95%CI: 3.96-15.91; OR = 0.09; 95%CI: 0.04-0.19). There was no significant difference in histological resection rate(OR = 1.65; 95%CI: 0.29-9.30) and procedure-related complication rate between the two groups (OR = 1.59; 95%CI: 0.92-2.73). The meta-analysis also showed that ESD was more time consuming than EMR.

Conclusion: Compared with EMR, ESD results in higher en bloc resection rate and lower local recurrence rate for the treatment of colorectal tumors, without increasing the procedure-related complications.

Citing Articles

Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection.

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PMID: 39132198 PMC: 11309798. DOI: 10.1055/s-0043-1770941.

Outcomes of Colorectal Endoscopic Submucosal Dissection for Elderly Patients: A Multicenter Study by the Honam Association for the Study of Intestinal Disease (HASID).

Jin B, Kim D, Oh H, Song H, Kim S, Myung D In Vivo. 2024; 38(3):1405-1411.

PMID: 38688593 PMC: 11059894. DOI: 10.21873/invivo.13582.

Endoscopic Resection Techniques.

Hoffman A, von Heesen M, Kollmar O, Kiesslich R Visc Med. 2024; 33(4):285-294.

PMID: 38500535 PMC: 10945325. DOI: 10.1159/000477923.

Endoscopic Submucosal Dissection Is Safe and Effective for Lesions Located at the Anorectal Junction: Analysis from Two Referral European Centers.

Figueiredo Ferreira M, Marques M, Morais R, Lemmers A, Macedo G, Santos-Antunes J GE Port J Gastroenterol. 2024; 31(1):41-47.

PMID: 38476304 PMC: 10928857. DOI: 10.1159/000528107.

Efficacy and safety of endoscopic submucosal dissection for colorectal dysplasia in patients with inflammatory bowel disease: a systematic review and meta-analysis.

Malik T, Sabesan V, Mohan B, Rahman A, Othman M, Draganov P Clin Endosc. 2024; 57(3):317-328.

PMID: 38419168 PMC: 11133987. DOI: 10.5946/ce.2023.205.

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