Immunotactoid Glomerulopathy with Fingerprint Immune Deposits. A Variant of Lupus Nephritis?

Overview

Journal Virchows Arch A Pathol Anat Histopathol

Specialty Anatomy & Histology

Date 1989 Jan 1

PMID 2500773

Citations 2

Authors

F M Lai

K N Lai

E K Li

J Y Sung

J S Tam

Affiliations

Soon will be listed here.

Abstract

Immunotactoid glomerulopathy is a distinct clinico-pathological entity which has recently been defined. The term immunotactoid refers to highly organized immune depositions appearing as rod-like microtubular structures in ultrastructural examination. We describe a patient with mixed connective tissue disease who demonstrates characteristic features of immunotactoid glomerulopathy. The diagnosis was made after excluding amyloidosis, cryoglobulinaemia and lupus nephritis. In addition to immunotactoid microtubules, ultrastructural examination also demonstrated presence of fingerprint depositions which were intimately mixed with immunotactoid structures. Fingerprint deposits have been described in lupus nephritis and cryoglobulin-related nephropathy, but rarely in other glomerulonephritis. These unique findings in our patient may suggest a previously unsuspected relationship between the syndrome of immunotactoid glomerulopathy and systemic lupus erythematosus.

Citing Articles

Nodular mesangial lesions, marked mesangiolysis, and fingerprint deposits of unknown origin in a patient with nephrotic syndrome: a unique combination of glomerular lesions.

Ohtani H, Wakui H, Komatsuda A, Okuyama S, Masai R, Maki N Clin Exp Nephrol. 2006; 10(2):140-5.

PMID: 16791402 DOI: 10.1007/s10157-006-0412-0.

Nonamyloidotic fibrillary glomerulopathy. Report of a case and review of the literature.

Billis A, Homsi E Int Urol Nephrol. 1991; 23(4):295-301.

PMID: 1938223 DOI: 10.1007/BF02549598.

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