Endomyocardial Fibrosis (EMF) in a Ugandan Child with Advanced Hepatosplenic Schistosomiasis: Coincidence or Connection?
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An association between late-stage hepatosplenic schistosomiasis and endomyocardial fibrosis (EMF) has been suggested but not proven. We present the case of a 12-year-old Ugandan boy with striking comorbidities, including advanced periportal fibrosis caused by Schistosoma mansoni infection and right ventricular EMF, and discuss the possible correlation between both diseases.
Endomyocardial fibrosis: recent advances and future therapeutic targets.
Mocumbi A, Hotta V, Bukhman G, Ntusi N, Yacoub M, Correia-de-Sa P Nat Rev Cardiol. 2025; .
PMID: 40011660 DOI: 10.1038/s41569-025-01138-x.
Sempere A, Salvador F, Mila L, Casas G, Dura-Miralles X, Sulleiro E PLoS Negl Trop Dis. 2024; 18(8):e0012410.
PMID: 39102438 PMC: 11326544. DOI: 10.1371/journal.pntd.0012410.
Aliku T, Rwebembera J, Lubega S, Zhang W, Lugero C, Namuyonga J Front Cardiovasc Med. 2022; 9:841346.
PMID: 35498040 PMC: 9051226. DOI: 10.3389/fcvm.2022.841346.
Endomyocardial Fibrosis: an Update After 70 Years.
Mocumbi A, Stothard J, Correia-de-Sa P, Yacoub M Curr Cardiol Rep. 2019; 21(11):148.
PMID: 31758352 DOI: 10.1007/s11886-019-1244-3.
Carranza-Rodriguez C, San-Roman-Sanchez D, Marrero-Santiago H, Hernandez-Cabrera M, Gil-Guillen C, Pisos-Alamo E PLoS Negl Trop Dis. 2017; 11(2):e0005403.
PMID: 28234952 PMC: 5342272. DOI: 10.1371/journal.pntd.0005403.