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Serum Adenosine Deaminase Activity in Cutaneous Anthrax

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Journal Med Sci Monit
Date 2014 Jul 7
PMID 24997584
Citations 1
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Abstract

Background: Adenosine deaminase (ADA) activity has been discovered in several inflammatory conditions; however, there are no data associated with cutaneous anthrax. The aim of this study was to investigate serum ADA activity in patients with cutaneous anthrax.

Material And Methods: Sixteen patients with cutaneous anthrax and 17 healthy controls were enrolled. We measured ADA activity; peripheral blood leukocyte, lymphocyte, neutrophil, and monocyte counts; erythrocyte sedimentation rate; and C reactive protein levels.

Results: Serum ADA activity was significantly higher in patients with cutaneous anthrax than in the controls (p<0.001). A positive correlation was observed between ADA activity and lymphocyte counts (r=0.589, p=0.021) in the patient group.

Conclusions: This study suggests that serum ADA could be used as a biochemical marker in cutaneous anthrax.

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Yu M, Zhou H, Li Q, Ding J, Shuai H, Zhang J Clin Appl Thromb Hemost. 2021; 27:1076029621999722.

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