Serum Adenosine Deaminase Activity in Cutaneous Anthrax
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Background: Adenosine deaminase (ADA) activity has been discovered in several inflammatory conditions; however, there are no data associated with cutaneous anthrax. The aim of this study was to investigate serum ADA activity in patients with cutaneous anthrax.
Material And Methods: Sixteen patients with cutaneous anthrax and 17 healthy controls were enrolled. We measured ADA activity; peripheral blood leukocyte, lymphocyte, neutrophil, and monocyte counts; erythrocyte sedimentation rate; and C reactive protein levels.
Results: Serum ADA activity was significantly higher in patients with cutaneous anthrax than in the controls (p<0.001). A positive correlation was observed between ADA activity and lymphocyte counts (r=0.589, p=0.021) in the patient group.
Conclusions: This study suggests that serum ADA could be used as a biochemical marker in cutaneous anthrax.
Yu M, Zhou H, Li Q, Ding J, Shuai H, Zhang J Clin Appl Thromb Hemost. 2021; 27:1076029621999722.
PMID: 33651650 PMC: 7930648. DOI: 10.1177/1076029621999722.