» Articles » PMID: 24997544

Renal Complications in Anorexia Nervosa

Overview
Publisher Springer
Date 2014 Jul 7
PMID 24997544
Citations 20
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose: Anorexia nervosa is a malady with possible long-lasting physiological consequences. Among these, little is known about the renal effects, which remain rarely investigated.

Methods: A literature review was conducted using electronic databases and manual search of relevant articles, discussing the renal impacts of anorexia nervosa.

Results: Renal failure has been described in malnourished patients, but the optimal non-invasive tool to assess the glomerular function rate in this population needs to be further evaluated. Significant disruptions in osmolar regulation, even in the absence of potomania, arise from multiple factors: hypothalamic dysfunction, intrinsic renal insufficiency, and use of psychotropic medications. Urinary urgency and nocturnal enuresis are frequent symptoms, rarely reported by patients. Among hydroelectrolytic disorders, hypokalemia is the most frequent, especially in settings of vomiting or medication misuse. Hyponatremia, hypomagnesemia, and hypophosphatemia may also be encountered. Urinary lithiases are relatively frequent as a consequence of dehydration, laxative use, or both.

Conclusion: Investigation and follow-up of the renal function are essential in patients with an eating disorder, especially when the illness has been present for a long time.

Citing Articles

Assessment of the renal function of patients with anorexia nervosa.

Miyahara H, Shigeyasu Y, Fujii C, Tanaka C, Hanzawa M, Sugihara A Biopsychosoc Med. 2024; 18(1):19.

PMID: 39343908 PMC: 11439319. DOI: 10.1186/s13030-024-00316-6.


Pediatric hospital utilization for patients with avoidant restrictive food intake disorder.

Milliren C, Crowley M, Carmody J, Bern E, Eldredge O, Richmond T J Eat Disord. 2024; 12(1):42.

PMID: 38528642 PMC: 10962111. DOI: 10.1186/s40337-024-00996-z.


Renal failure following insulin purging in atypical anorexia nervosa and type 1 diabetes mellitus.

Rometsch C, Guthoff M, Zipfel S, Stengel A Front Psychiatry. 2023; 14:1325021.

PMID: 38152359 PMC: 10752605. DOI: 10.3389/fpsyt.2023.1325021.


Hypercapnia in hospitalized children and adolescents with anorexia nervosa as a predictive marker for readmission: a prospective study.

Viano-Nogueira P, Aparicio-Lopez C, Prieto-Campo A, Moron-Nozaleda G, Camarneiro-Silva R, Graell-Berna M Eat Weight Disord. 2023; 28(1):94.

PMID: 37921895 PMC: 10624702. DOI: 10.1007/s40519-023-01624-6.


How to Monitor Hydration Status and Urine Dilution in Patients with Nephrolithiasis.

Travers S, Prot-Bertoye C, Daudon M, Courbebaisse M, Baron S Nutrients. 2023; 15(7).

PMID: 37049482 PMC: 10097240. DOI: 10.3390/nu15071642.


References
1.
Kanbur N, Pinhas L, Lorenzo A, Farhat W, Licht C, Katzman D . Nocturnal enuresis in adolescents with anorexia nervosa: prevalence, potential causes, and pathophysiology. Int J Eat Disord. 2010; 44(4):349-55. DOI: 10.1002/eat.20822. View

2.
Russell G, BRUCE J . Impaired water diuresis in patients with anorexia nervosa. Am J Med. 1966; 40(1):38-48. DOI: 10.1016/0002-9343(66)90185-9. View

3.
Daudon M . [Epidemiology of nephrolithiasis in France]. Ann Urol (Paris). 2006; 39(6):209-31. DOI: 10.1016/j.anuro.2005.09.007. View

4.
Fabbian F, Pala M, Scanelli G, Manzato E, Longhini C, Portaluppi F . Estimation of renal function in patients with eating disorders. Int J Eat Disord. 2010; 44(3):233-7. DOI: 10.1002/eat.20813. View

5.
Torres V, Young Jr W, Offord K, Hattery R . Association of hypokalemia, aldosteronism, and renal cysts. N Engl J Med. 1990; 322(6):345-51. DOI: 10.1056/NEJM199002083220601. View