Influence of Angulation on Metacarpal Bone Mineral Density Measurements Using Digital X-ray Radiogrammetry

Overview

Journal Int J Comput Assist Radiol Surg

Publisher Springer

Specialties General Surgery
Radiology

Date 2014 Jul 4

PMID 24989966

Citations 3

Authors

Alexander Pfeil

Diane M Renz

Rosemarie Frober

Andreas Hansch

Gabriele Lehmann

Julia Sommerfeld

Ansgar Malich

Gunter Wolf

Joachim Bottcher

Affiliations

Soon will be listed here.

Abstract

Objective: Digital X-ray radiogrammetry (DXR) is a computer-assisted technique used to quantify cortical bone density of the metacarpals. The influence of metacarpal bone rotation and type of cast material on bone mineral density (BMD) measurements using the DXR technique was tested.

Methods: The bone mineral density of the hand was measured by DXR, and rotation error (DXR-RE) as coefficients of variation were calculated, to verify reliability and reproducibility of this radiogeometric technique to assess in particular minor disease-related changes in the metacarpal bone mass. The reproducibility of the DXR measurements was also investigated using different cast materials (mull, elastic, and plastic).

Results: There were no significant changes in absolute values of DXR-BMD observed between 0 to [Formula: see text] angulation. The relative DXR-RE ranged between 0 % (degree 1) and 0.70 % (degrees 15 and 19) for DXR-BMD. Regarding the different cast materials, DXR-BMD revealed a coefficient of variation with 0.41 % (mull cast) and 0.21 % (elastic cast). For the plastic cast, the DXR technique was not able to perform an analysis of DXR-BMD.

Conclusion: The study revealed no significant influence of metacarpal rotation on the measurements of metacarpal bone mineral density as estimated by DXR. DXR measurements are not optimal when cast material is used. DXR can accurately quantify periarticular cortical bone mass. This is significant especially for rheumatoid arthritis and related conditions where X-ray imaging of arthritic hands with varying degrees of deformity is performed.

Citing Articles

Metacarpal bone loss in patients with rheumatoid arthritis estimated by a new Digital X-ray Radiogrammetry method - initial results.

Pfeil A, Thodberg H, Renz D, Reinhardt L, Oelzner P, Wolf G BMC Musculoskelet Disord. 2017; 18(1):6.

PMID: 28061837 PMC: 5216610. DOI: 10.1186/s12891-016-1348-5.

Psoriatic arthritis is associated with bone loss of the metacarpals.

Pfeil A, Krojniak L, Renz D, Reinhardt L, Franz M, Oelzner P Arthritis Res Ther. 2016; 18(1):248.

PMID: 27782850 PMC: 5080685. DOI: 10.1186/s13075-016-1145-4.

Digital X-ray radiogrammetry and its sensitivity and specificity for the identification of rheumatoid arthritis-related cortical hand bone loss.

Pfeil A, Haugeberg G, Renz D, Reinhardt L, Jung C, Franz M J Bone Miner Metab. 2016; 35(2):192-198.

PMID: 26979320 DOI: 10.1007/s00774-016-0741-3.

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