Previous Experience Disrupts D-amphetamine-induced Stereotypic Diving in Rats

Overview

Journal Psychopharmacology (Berl)

Specialty Pharmacology

Date 1989 Jan 1

PMID 2498942

Authors

A D Petree

T L DeVietti

Affiliations

Soon will be listed here.

Abstract

Rats given d-amphetamine and placed in a tank of water repeatedly dive towards the bottom of the tank. Two experiments investigated this stereotypy. The first established a dose-response function for the stereotypy and the second showed that experience with the apparatus prior to drug administration disrupted the stereotypy. The latter result is consistent with the findings of previous work and thus provides a degree of generality for the role of experience interacting with CNS drugs to induce stereotypies.

References

RANDRUP A, MUNKVAD I . Stereotyped activities produced by amphetamine in several animal species and man. Psychopharmacologia. 1967; 11(4):300-10. DOI: 10.1007/BF00404607. View

Dickinson S, Andrews C, Curzon G . The effects of lesions produced by 5,7-dihydroxytryptamine on 5-hydroxytryptamine-mediated behaviour induced by amphetamine in large doses in the rat. Neuropharmacology. 1984; 23(4):423-9. DOI: 10.1016/0028-3908(84)90250-8. View

Curzon G, Fernando J, Lees A . Backward walking and circling: behavioural responses induced by drug treatments which cause simultaneous release of catecholamines and 5-hydroxytryptamine. Br J Pharmacol. 1979; 66(4):573-9. PMC: 2043578. DOI: 10.1111/j.1476-5381.1979.tb13696.x. View

Szechtman H, Ornstein K, Teitelbaum P, Golani I . The morphogenesis of stereotyped behavior induced by the dopamine receptor agonist apomorphine in the laboratory rat. Neuroscience. 1985; 14(3):783-98. DOI: 10.1016/0306-4522(85)90143-5. View

Schallert T, De Ryck M, Teitelbaum P . Atropine stereotypy as a behavioral trap: a movement subsystem and electroencephalographic analysis. J Comp Physiol Psychol. 1980; 94(1):1-24. DOI: 10.1037/h0077656. View

COLE S . Experimental effects of amphetamine: a review. Psychol Bull. 1967; 68(2):81-90. DOI: 10.1037/h0020185. View

Holmgren B, URBA-HOLMGREN R, Valdes M . Relative role of catecholamines in head-shaking of infant rats. Pharmacol Biochem Behav. 1976; 5(1):29-34. DOI: 10.1016/0091-3057(76)90284-7. View

Sahakian B, Robbins T, Morgan M, Iversen S . The effects of psychomotor stimulants on stereotypy and locomotor activity in socially-deprived and control rats. Brain Res. 1975; 84(2):195-205. DOI: 10.1016/0006-8993(75)90975-0. View

Andrews C, Fernando J, Curzon G . Differential involvement of dopamine-containing tracts in 5-hydroxytryptamine-dependent behaviours caused by amphetamine in large doses. Neuropharmacology. 1982; 21(1):63-8. DOI: 10.1016/0028-3908(82)90212-x. View

10.

Dickinson S, Curzon G . Roles of dopamine and 5-hydroxytryptamine in stereotyped and non-stereotyped behaviour. Neuropharmacology. 1983; 22(7):805-12. DOI: 10.1016/0028-3908(83)90124-7. View

11.

Jerussi T, Glick S . Drug-induced rotation in rats without lesions: behavioral and neurochemical indices of a normal asymmetry in nigro-striatal function. Psychopharmacology (Berl). 1976; 47(3):249-60. DOI: 10.1007/BF00427609. View

12.

Quock R, Horita A . Differentiaton of neuropharmacological actions of apomorphine and d-amphetamine. Pharmacol Biochem Behav. 1976; 5(6):627-31. DOI: 10.1016/0091-3057(76)90303-8. View

13.

DeVietti T, Pellis S, Pellis V, Teitelbaum P . Previous experience disrupts atropine-induced stereotyped "trapping" in rats. Behav Neurosci. 1985; 99(6):1128-41. DOI: 10.1037//0735-7044.99.6.1128. View

14.

COLE S . Interaction of arena size with different measures of amphetamine effects. Pharmacol Biochem Behav. 1977; 7(2):181-4. DOI: 10.1016/0091-3057(77)90205-2. View

15.

Sirkin D, Teitelbaum P . The pontine reticular formation is part of the output pathway for amphetamine- and apomorphine-induced lateral head movements: evidence from experimental lesions in the rat. Brain Res. 1983; 260(2):291-6. DOI: 10.1016/0006-8993(83)90683-2. View

16.

Fog R . On stereotypy and catalepsy: studies on the effect of amphetamines and neuroleptics in rats. Acta Neurol Scand Suppl. 1972; 50:3-66. View