Effect of Methadone Maintenance Therapy on Anthropometric Indices in Opioid Dependent Patients

Overview

Journal Int J High Risk Behav Addict

Publisher Brieflands

Specialty Psychology

Date 2014 Jun 28

PMID 24971244

Citations 10

Authors

Farzaneh Montazerifar

Mansour Karajibani

Kobra Lashkaripour

Affiliations

Soon will be listed here.

Abstract

Background: Opium abuse significantly affects the nutritional status of users and frequently leads to undernourishment. Methadone maintenance therapy has been used as one of the possible ways to prevent of infection diseases such as HIV and hepatitis B and C and improve the quality of life in opioid-dependent patients.

Objectives: The aim of this study was to assess the anthropometric and socio-demographic characteristics of opium addicted persons before and after 8 weeks of methadone maintenance therapy (MMT).

Patients And Methods: A clinical cross-sectional study was carried out on 55 opium users (15 women and 40 men; mean aged 31.6 ± 10 years), dependent on opium and its derivatives at the Addiction Treatment Clinic of the Baharan psychiatric Hospital, Zahedan, Sistan and Baluchistan Province, Iran, in 2011. The patients were examined before and after 8 weeks MMT. Weight and height of participants were taken and the body mass index (BMI) was calculated.

Results: Body weight increased significantly from 61.4 ± 14.4 to 65.3 ± 14.2 kg and BMI from 21.4 ± 4.2 to 23 ± 5.6 (kg/m(2)) after 8 weeks of methadone maintenance therapy in opium users (P < 0.01). The percentages of underweight, overweight and obese patients were; 27.3%, 18.2% and 3.6%, respectively pre-MMT, and 12.7%, 18.2% and 7.2%, respectively after MMT.

Conclusions: The study shows that methadone Maintenance Therapy led to improvements in nutritional status.

Citing Articles

Weight change among patients engaged in medication treatment for opioid use disorder: a scoping review.

Carr M, Lou R, Macdonald-Gagnon G, Peltier M, Funaro M, Martino S Am J Drug Alcohol Abuse. 2023; 49(5):551-565.

PMID: 37200510 PMC: 10840392. DOI: 10.1080/00952990.2023.2207720.

Patterns and Determinants of Weight Gain among People Who Use Drugs Undergoing Treatment for Recovery in Lebanon.

Mahboub N, Rizk R, Farsoun C, de Vries N Nutrients. 2023; 15(4).

PMID: 36839347 PMC: 9961335. DOI: 10.3390/nu15040990.

Examination of the nutritional intake of patients undergoing opioid replacement therapy: A systematic review.

Waddington F, Naunton M, Thomas J, Kyle G, Wheatley B, Oguoma V Nutr Diet. 2022; 80(1):55-64.

PMID: 36535902 PMC: 10107466. DOI: 10.1111/1747-0080.12784.

Sex differences in weight gain during medication-based treatment for opioid use disorder: A meta-analysis and retrospective analysis of clinical trial data.

Manza P, Kroll D, McPherson K, Johnson A, Dennis E, Hu L Drug Alcohol Depend. 2022; 238:109575.

PMID: 35868182 PMC: 9444983. DOI: 10.1016/j.drugalcdep.2022.109575.

OpiTrack: A Wearable-based Clinical Opioid Use Tracker with Temporal Convolutional Attention Networks.

Gullapalli B, Carreiro S, Chapman B, Ganesan D, Sjoquist J, Rahman T Proc ACM Interact Mob Wearable Ubiquitous Technol. 2022; 5(3).

PMID: 35291374 PMC: 8920039. DOI: 10.1145/3478107.

References

Morabia A, Fabre J, Chee E, Zeger S, Orsat E, Robert A . Diet and opiate addiction: a quantitative assessment of the diet of non-institutionalized opiate addicts. Br J Addict. 1989; 84(2):173-80. DOI: 10.1111/j.1360-0443.1989.tb00566.x. View

Ghosh A . Comparison of anthropometric, metabolic and dietary fatty acids profiles in lean and obese dyslipidaemic Asian Indian male subjects. Eur J Clin Nutr. 2006; 61(3):412-9. DOI: 10.1038/sj.ejcn.1602534. View

Bahat G, Tufan F, Saka B, Akin S, Ozkaya H, Yucel N . Which body mass index (BMI) is better in the elderly for functional status?. Arch Gerontol Geriatr. 2011; 54(1):78-81. DOI: 10.1016/j.archger.2011.04.019. View

Cook Z, Kirk S, Lawrenson S, Sandford S . Use of BMI in the assessment of undernutrition in older subjects: reflecting on practice. Proc Nutr Soc. 2005; 64(3):313-7. DOI: 10.1079/pns2005437. View

KABRT J, Wilczek H, Svobodova J, Haluzik M, Kotrlikova E . [Nutritional status of drug addicts in a methadone program]. Cas Lek Cesk. 2000; 138(22):693-5. View

Mysels D, Vosburg S, Benga I, Levin F, Sullivan M . Course of weight change during naltrexone versus methadone maintenance for opioid-dependent patients. J Opioid Manag. 2011; 7(1):47-53. PMC: 3111025. DOI: 10.5055/jom.2011.0048. View

. Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee. World Health Organ Tech Rep Ser. 1995; 854:1-452. View

Islam S, Hossain K, Ahmed A, Ahsan M . Nutritional status of drug addicts undergoing detoxification: prevalence of malnutrition and influence of illicit drugs and lifestyle. Br J Nutr. 2002; 88(5):507-13. DOI: 10.1079/BJN2002702. View

Kheradmand A, Banazadeh N, Abedi H . Physical effects of methadone maintenance treatment from the standpoint of clients. Addict Health. 2014; 2(3-4):66-73. PMC: 3905514. View

10.

Zador D, Lyons Wall P, Webster I . High sugar intake in a group of women on methadone maintenance in south western Sydney, Australia. Addiction. 1996; 91(7):1053-61. View

11.

Forrester J, Tucker K, Gorbach S . Dietary intake and body mass index in HIV-positive and HIV-negative drug abusers of Hispanic ethnicity. Public Health Nutr. 2004; 7(7):863-70. DOI: 10.1079/phn2004617. View

12.

Forrester J . Nutritional Alterations in Drug Abusers With and Without HIV. Am J Infect Dis. 2007; 2(3):173-179. PMC: 1820890. View

13.

Housova J, Wilczek H, Haluzik M, Kremen J, Krizova J, Haluzik M . Adipocyte-derived hormones in heroin addicts: the influence of methadone maintenance treatment. Physiol Res. 2005; 54(1):73-78. DOI: 10.33549/physiolres.930568. View

14.

Saeland M, Haugen M, Eriksen F, Smehaugen A, Wandel M, Bohmer T . Living as a drug addict in Oslo, Norway--a study focusing on nutrition and health. Public Health Nutr. 2008; 12(5):630-6. DOI: 10.1017/S1368980008002553. View

15.

Wilczek H, Haluzik M, Svobodova J, Parizkova J . [Serum leptin levels in patients with heroin addiction, the effect of one year of methadone substitution]. Vnitr Lek. 2004; 50(4):282-5. View