Nanobiotechnology and Bone Regeneration: a Mini-review

Overview

Journal Int Orthop

Specialty Orthopedics

Date 2014 Jun 26

PMID 24962293

Citations 17

Authors

Nadomir Gusic

Alan Ivkovic

John VaFaye

Andreja Vukasovic

Jana Ivkovic

Damir Hudetz

Sasa Jankovic

Affiliations

Soon will be listed here.

Abstract

The purpose of this paper is to review current developments in bone tissue engineering, with special focus on the promising role of nanobiotechnology. This unique fusion between nanotechnology and biotechnology offers unprecedented possibilities in studying and modulating biological processes on a molecular and atomic scale. First we discuss the multiscale hierarchical structure of bone and its implication on the design of new scaffolds and delivery systems. Then we briefly present different types of nanostructured scaffolds, and finally we conclude with nanoparticle delivery systems and their potential use in promoting bone regeneration. This review is not meant to be exhaustive and comprehensive, but aims to highlight concepts and key advances in the field of nanobiotechnology and bone regeneration.

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