Pulmonary Thromboembolism Associated with Procainamide Induced Lupus Syndrome and Anticardiolipin Antibodies

Overview

Journal Ann Rheum Dis

Specialty Rheumatology

Date 1989 Mar 1

PMID 2494958

Citations 5

Authors

R A Asherson

J Zulman

G R Hughes

Affiliations

Soon will be listed here.

Abstract

Procainamide is the commonest cause of a drug induced lupus syndrome. Long term administration of this compound may induce a variety of immunological abnormalities, including antinuclear antibodies. Uncommonly, 'lupus anticoagulants' have been demonstrated in the absence of other evidence of drug induced lupus. Details of a 67 year old man who developed not only drug induced lupus but also antiphospholipid antibodies which were associated with multiple pulmonary thromboemboli after the administration of procainamide are recorded.

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