A Fluorescent Light-up Probe with AIE Characteristics for Specific Mitochondrial Imaging to Identify Differentiating Brown Adipose Cells

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2014 Jun 19

PMID 24940580

Citations 7

Authors

Meng Gao

Choon Kiat Sim

Chris Wai Tung Leung

Qinglian Hu

Guangxue Feng

Feng Xu

Ben Zhong Tang

Bin Liu

Affiliations

Soon will be listed here.

Abstract

We report the design and synthesis of a specific mitochondrial fluorescent probe AIE-MitoGreen-1 with AIE characteristics to monitor the mitochondrial morphology changes and identify the differentiation process of living brown adipose cells. The probe AIE-MitoGreen-1 has significant advantages such as high cellpermeability, good mitochondrial retention, low background fluorescence, large Stokes shift, and low toxicity.

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