Synchronous Primary Malignancies of the Male Urogenital Tract

Overview

Journal Can Urol Assoc J

Specialty Urology

Date 2014 Jun 19

PMID 24940463

Citations 2

Authors

Abdelmounaim Qarro

Abdelghani Ammani

Khalil Bazine

Mohammed Najoui

Jamaleddine Samir

Mohammed Alami

Affiliations

Soon will be listed here.

Abstract

The finding of prostate cancer after a cystoprostatectomy for a bladder tumour can occur in up to 70% of cases. The incidence of prostate cancer in patients with a bladder tumour is 18 times higher than in the general population; moreover, the incidence of bladder cancer in patients with prostate cancer is 19 times higher than in the general population. This association can be explained by the common embryological origin of these organs, with molecular similarities. Other similarities between these two cancers are noted. They are multifocal and may be secondary to urinary stasis. However, this association does not seem responsible for an increased risk of progression of both diseases. The prognosis is related to the extension of each cancer. The stage and grade of bladder cancer are, in terms of prognosis, greater than those of prostate cancer. Most often, this is insignificant prostate cancer. Despite this, the prostate-specific antigen test should be administered to monitor patients after cystoprostatectomy.

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