Iodine and Thyroid Function

Overview

Journal Ann Pediatr Endocrinol Metab

Specialty Pediatrics

Date 2014 Jun 14

PMID 24926457

Citations 51

Authors

Hye Rim Chung

Affiliations

Soon will be listed here.

Abstract

Severe iodine deficiency causes hypothyroidism that results in impaired somatic growth and motor development in children. Mild and moderate iodine deficiencies cause multifocal autonomous growth of thyroid, which results in thyrotoxicosis. On the other hand, iodine excess is associated with the development of hypothyroidism and thyroid autoimmunity. In areas of iodine deficiency, a sudden increase in iodine intake is associated with transient hyperthyroidism. Recent studies demonstrated that long-term thyroid function of subjects who experienced both iodine deficiency and iodine excess during childhood tended to be abnormal despite optimization of their current iodine intake. Iodine status in the Korean Peninsula is very unique because people in the Republic of Korea have been shown to have predominantly excessive iodine levels, whereas the Democratic People's Republic of Korea is known to be an iodine-deficient area. Further research is warranted to verify the optimal ranges of iodine intake and to clarify the effects of iodine intake on thyroid disorders in the Korean Peninsula.

Citing Articles

Excessive Iodine Intake During Lactation Is Not Related to the Incidence of Thyroid Disease: A 3-Year Follow-Up Study.

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Organic Iodine Improves the Growth Performance and Gut Health of Fujian Yellow Rabbits.

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Revealing the genetic complexity of hypothyroidism: integrating complementary association methods.

Zucker R, Kovalerchik M, Stern A, Kaufman H, Linial M Front Genet. 2024; 15:1409226.

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In vitro and in vivo investigation of a thyroid hormone system-specific interaction with triazoles.

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Dietary Patterns and Hypothyroidism in U.S. Adult Population.

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