Characteristics and Chemical Compositions of Propolis from Ethiopia

Overview

Journal Springerplus

Date 2014 Jun 14

PMID 24926420

Citations 13

Authors

Ahmed I Rushdi

Nuru Adgaba

Noofal I M Bayaqoob

Ahmed Al-Khazim

Bernd I T Simoneit

Aarif H El-Mubarak

Khalid F Al-Mutlaq

Affiliations

Soon will be listed here.

Abstract

Introduction: Propolis is a sticky material mixed by honeybees to utilize it in protecting their hives from infection by bacteria and fungi. The therapeutic properties of propolis are due to its chemical composition with bio-active compounds; therefore, researchers are interested in studying its chemical constituents and biological properties. The main objective of this study is to determine the chemical compositions, characteristics and relative concentrations of organic compounds in the extractable organic matter of propolis samples collected from four different areas in Ethiopia.

Results: The propolis samples were extracted with a mixture of dichloromethane and methanol and analyzed by gas chromatography-mass spectrometry (GC-MS).The results showed that the total extract yields ranged from 27.2% to 64.2% (46.7 ± 19.1%). The major compounds were triterpenoids (85.5 ± 15.0% of the total extracts, mainly α-, β-amyrins and amyryl acetates), n-alkanes (5.8 ± 7.5%), n-alkenes (6.2 ± 7.0%,), methyl n-alkanoates (0.4 ± 0.2%), and long chain wax esters (0.3 to 2.1%).

Conclusion: The chemical compositions of these propolis samples indicate that they are potential sources of natural bio-active compounds for biological and pharmacological applications.

Citing Articles

New insights of propolis nanoformulation and its therapeutic potential in human diseases.

Kustiawan P, Syaifie P, Siregar K, Ibadillah D, Mardliyati E ADMET DMPK. 2024; 12(1):1-26.

PMID: 38560717 PMC: 10974817. DOI: 10.5599/admet.2128.

The Oral Wound Healing Potential of Thai Propolis Based on Its Antioxidant Activity and Stimulation of Oral Fibroblast Migration and Proliferation.

Jongjitaree S, Koontongkaew S, Niyomtham N, Yingyongnarongkul B, Utispan K Evid Based Complement Alternat Med. 2022; 2022:3503164.

PMID: 35664934 PMC: 9162842. DOI: 10.1155/2022/3503164.

Chemical Variability and Pharmacological Potential of Propolis as a Source for the Development of New Pharmaceutical Products.

Wieczorek P, Hudz N, Yezerska O, Horcinova-Sedlackova V, Shanaida M, Korytniuk O Molecules. 2022; 27(5).

PMID: 35268700 PMC: 8911684. DOI: 10.3390/molecules27051600.

Determination of Phenolic Compounds in Various Propolis Samples Collected from an African and an Asian Region and Their Impact on Antioxidant and Antibacterial Activities.

Touzani S, Imtara H, Katekhaye S, Mechchate H, Ouassou H, Alqahtani A Molecules. 2021; 26(15).

PMID: 34361742 PMC: 8347760. DOI: 10.3390/molecules26154589.

Potential Role of Propolis in the Prevention and Treatment of Metabolic Diseases.

Balica G, Vostinaru O, Stefanescu C, Mogosan C, Iaru I, Cristina A Plants (Basel). 2021; 10(5).

PMID: 33925692 PMC: 8144987. DOI: 10.3390/plants10050883.

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