A Molecular Transport Medium for Collection, Inactivation, Transport, and Detection of Mycobacterium Tuberculosis
Overview
Affiliations
In many parts of the world, the diagnosis of tuberculosis (TB) has rapidly shifted to molecular detection and sequencing formats. The collection and transport of Mycobacterium tuberculosis specimens thus remains a challenging problem where TB is common and the infrastructure required for ensuring sample integrity is lacking. PrimeStore(®) Molecular Transport Medium (MTM) addresses this problem, rapidly inactivating/killing M. tuberculosis while preserving genomic DNA even at elevated temperatures for subsequent downstream molecular analysis.
Evolution of Laboratory Diagnosis of Tuberculosis.
Zaporojan N, Negrean R, Hodisan R, Zaporojan C, Csep A, Zaha D Clin Pract. 2024; 14(2):388-416.
PMID: 38525709 PMC: 10961697. DOI: 10.3390/clinpract14020030.
Zeineldin M, Lehman K, Camp P, Farrell D, Thacker T Pathogens. 2023; 12(8).
PMID: 37623932 PMC: 10458061. DOI: 10.3390/pathogens12080972.
Chibolela M, de Haas P, Klinkenberg E, Kosloff B, Chunda-Liyoka C, Lungu P Int J Tuberc Lung Dis. 2023; 27(8):612-618.
PMID: 37491746 PMC: 10365563. DOI: 10.5588/ijtld.22.0530.
Anthwal D, Gupta R, Singhal R, Bhalla M, Verma A, Umar Khayyam K ERJ Open Res. 2021; 7(3).
PMID: 34350282 PMC: 8326685. DOI: 10.1183/23120541.00137-2021.
Myers N, Han T, Li M, Brewer G, Harper M, Mainelis G J Occup Environ Hyg. 2021; 18(9):461-475.
PMID: 34197274 PMC: 9563239. DOI: 10.1080/15459624.2021.1948047.