Evidence-based Management of Necrotizing Pancreatitis

Overview

Journal Curr Treat Options Gastroenterol

Specialty Gastroenterology

Date 2014 Jun 5

PMID 24894271

Citations 1

Authors

Diana A Whitehead

Timothy B Gardner

Affiliations

Soon will be listed here.

Abstract

Pancreatic necrosis may result as a complication of acute pancreatitis, often causing significant morbidity and mortality. There are many recommendations concerning the management of pancreatic necrosis, including non-operative management with supportive care and antibiotics, computed tomography (CT)-guided percutaneous drainage, endoscopic transluminal drainage, and operative necrosectomy. Historically, pancreatic necrosis has been treated surgically. However, surgical management of pancreatic necrosis is associated with high mortality (6-28 %) and morbidity (19-62 %). Thus, endoscopic therapy has emerged as a relatively new minimally invasive technique for treating infected and/or symptomatic pancreatic necrosis in the last decade. Although there have been two randomized trials comparing endoscopic transluminal drainage versus operative necrosectomy, there is little data regarding timing, indication, and outcomes of these procedures.

Citing Articles

Pancreatic endotherapy and necrosectomy.

Pannala R, Ross A Curr Treat Options Gastroenterol. 2015; 13(2):185-97.

PMID: 25773605 DOI: 10.1007/s11938-015-0048-9.

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