» Articles » PMID: 24880443

Effect of Erythrinamu Lungu on Anxiety During Extraction of Third Molars

Overview
Specialty Dentistry
Date 2014 Jun 2
PMID 24880443
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

Objectives: The aim of the present study was to evaluate the effect of Erythrinamu lungu on the control of dental anxiety in patients who had under gone bilateral extraction of asymptomatic, impacted mandibular third molars.

Material And Methods: In a randomized, double-blind, crossover study, 30 healthy volunteers (5 men and 25 women, over 18 years of age), received either 500mg of E.mulungu (MulunguMatusa®) or 500 mg of placebo, p.o., one hour before surgical procedure. The level ofanxiety was assessed through questionnaire sand physical parameters, such as blood pressure, heart rate andoxygen saturation. Data were analyzed by Chi-square test, ANOVA (Tukey test) and Friedman with significance level of 5%.

Results: A higher preference (Chi-square, p = 0.0062) for E. mulungu was observed for both genders. Volunteers with higher anxiety levels tended to to prefer E. mulungu. No statistically significant differences were verified in blood pressure (one-way ANOVA, p = 0.1259), heart rate (Friedman, p> 0.05) and oxygen saturation (Friedman, p = 0.7664) among periods and types of treatments.

Conclusions: E. mulungu showed an anxiolytic effect without significant changes in physiological parameters. It could be considered as an alternative to control the anxiety in adult patients undergoing mandibular thirdmolars surgery.

Citing Articles

Pharmacology activity, toxicity, and clinical trials of Erythrina genus plants (Fabaceae): an evidence-based review.

Susilawati E, Levita J, Susilawati Y, Sumiwi S Front Pharmacol. 2023; 14:1281150.

PMID: 38044940 PMC: 10690608. DOI: 10.3389/fphar.2023.1281150.


Effectiveness and safety of oral sedation in adult patients undergoing dental procedures: a systematic review.

Araujo J, Bergamaschi C, Lopes L, Guimaraes C, de Andrade N, Ramacciato J BMJ Open. 2021; 11(1):e043363.

PMID: 33495257 PMC: 7839856. DOI: 10.1136/bmjopen-2020-043363.


Herbal medicines as anxiolytics prior to third molar surgical extraction. A randomized controlled clinical trial.

da Cunha R, Amorim K, Gercina A, de Oliveira A, Menezes L, Groppo F Clin Oral Investig. 2020; 25(3):1579-1586.

PMID: 32951121 DOI: 10.1007/s00784-020-03468-1.

References
1.
Studer F, Gratz K, Mutzbauer T . Comparison of clonidine and midazolam as anxiolytic premedication before wisdom tooth surgery: a randomized, double-blind, crossover pilot study. Oral Maxillofac Surg. 2012; 16(4):341-7. DOI: 10.1007/s10006-012-0319-8. View

2.
Almendros-Marques N, Berini-Aytes L, Gay-Escoda C . Evaluation of intraexaminer and interexaminer agreement on classifying lower third molars according to the systems of Pell and Gregory and of Winter. J Oral Maxillofac Surg. 2008; 66(5):893-9. DOI: 10.1016/j.joms.2007.09.011. View

3.
Rosa D, Faggion S, Gavin A, Anderson de Souza M, Fachim H, dos Santos W . Erysothrine, an alkaloid extracted from flowers of Erythrina mulungu Mart. ex Benth: evaluating its anticonvulsant and anxiolytic potential. Epilepsy Behav. 2012; 23(3):205-12. DOI: 10.1016/j.yebeh.2012.01.003. View

4.
Jansma J, Schoen P, Raghoebar G, Vissink A . [Dentoalveolar surgery for the dentist: removal of teeth and root tips]. Ned Tijdschr Tandheelkd. 2004; 111(4):128-32. View

5.
Haas D . Alternative mandibular nerve block techniques: a review of the Gow-Gates and Akinosi-Vazirani closed-mouth mandibular nerve block techniques. J Am Dent Assoc. 2011; 142 Suppl 3:8S-12S. DOI: 10.14219/jada.archive.2011.0341. View