Measurement of Lens Autofluorescence for Diabetes Screening

Overview

Journal J Diabetes Sci Technol

Specialty Endocrinology

Date 2014 May 31

PMID 24876537

Citations 4

Authors

Alin Stirban

Affiliations

Soon will be listed here.

Abstract

Many efforts have been made lately to develop cost-effective, simple, and reproducible tests for diabetes screening besides the already established fasting plasma glucose, the oral glucose tolerance test, and the glycated hemoglobin A1. Several tests have been proposed lately, based on the measurement of the so-called advanced glycation endproducts (AGEs). AGEs production is exacerbated during hyperglycemia, and their accumulation in different tissues reflects the degree and duration of dysglycemia. The human lens represents a tissue where AGEs accumulation can be particularly well assessed. The present article comments on the article by Cahn et al. published in this issue of the Journal of Diabetes Science and Technology. Cahn and coauthors tested a new scanning confocal biomicroscope for its accuracy to detect noninvasively subjects with diabetes or at risk for developing diabetes.

Citing Articles

Clinical value of noninvasive lens advanced glycation end product detection in early screening and severity evaluation of patients with diabetic kidney disease.

Zheng X, Gao Y, Huang Y, Dong R, Yang M, Zhang X BMC Nephrol. 2023; 24(1):379.

PMID: 38115082 PMC: 10731831. DOI: 10.1186/s12882-023-03428-3.

Long-term development of lens fluorescence in a twin cohort: Heritability and effects of age and lifestyle.

Bjerager J, Dabbah S, Belmouhand M, Kessel L, Hougaard J, Rothenbuehler S PLoS One. 2022; 17(5):e0268458.

PMID: 35617652 PMC: 9135443. DOI: 10.1371/journal.pone.0268458.

Lens fluorescence and skin fluorescence in the Copenhagen Twin Cohort Eye Study: Covariates and heritability.

Bjerager J, Dabbah S, Belmouhand M, Rothenbuehler S, Sander B, Larsen M PLoS One. 2021; 16(9):e0256975.

PMID: 34499644 PMC: 8428679. DOI: 10.1371/journal.pone.0256975.

Skin AGEs and diabetic neuropathy.

Papachristou S, Pafili K, Papanas N BMC Endocr Disord. 2021; 21(1):28.

PMID: 33622304 PMC: 7903740. DOI: 10.1186/s12902-021-00697-7.

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