Weaning-induced Cardiac Dysfunction: Where Are We Today?

Overview

Journal Intensive Care Med

Specialty Critical Care

Date 2014 May 28

PMID 24861350

Citations 33

Authors

Jean-Louis Teboul

Affiliations

Soon will be listed here.

Abstract

Introduction: The concept of weaning-induced cardiac dysfunction emerged 26 years ago with the publication of a clinical study conducted by François Lemaire and collaborators.

Objectives: One objective of this article is to remember the results and the historical context under which our pivotal study was conducted. Another objective is to review some of the subsequent studies that aimed to analyze the underlying mechanisms, to noninvasively detect the cardiac origin of weaning failure, and to propose specific therapies enabling weaning success.

Conclusion: Weaning-induced cardiac dysfunction has become an established cause of weaning failure. Underlying mechanisms may differ from one patient to another. Important progress has already been made in its diagnosis thanks to relevant clinical research studies. Ongoing and future technological advances in ultrasonography and in biomarker research should certainly help in diagnosing weaning induced-pulmonary edema and in identifying the main mechanisms responsible for its development. Progress on appropriate therapeutic options on an individual basis is still expected.

Citing Articles

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Jozwiak M, Teboul J Ann Intensive Care. 2024; 14(1):122.

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The Value of Ischemic Cardiac Biomarkers to Predict Spontaneous Breathing Trial or Extubation Failure: A Systematic Review.

Groenland C, Blijleven M, Ramzi I, Dubois E, Heunks L, Endeman H J Clin Med. 2024; 13(11).

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Combined cardiac, lung, and diaphragm ultrasound for predicting weaning failure during spontaneous breathing trial.

Song J, Luo Q, Lai X, Hu W, Yu Y, Wang M Ann Intensive Care. 2024; 14(1):60.

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The Role of Ultrasonography in the Process of Weaning from Mechanical Ventilation in Critically Ill Patients.

Al-Husinat L, Jouryyeh B, Rawashdeh A, Robba C, Silva P, Rocco P Diagnostics (Basel). 2024; 14(4).

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Cardiopulmonary interactions during ventilator weaning.

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