Lubrication of Selected Salivary Molecules and Artificial Salivas

Overview

Journal Dysphagia

Date 1989 Jan 1

PMID 2484182

Citations 5

Authors

A Aguirre

B Mendoza

M S Reddy

F A Scannapieco

M J LeVine

M N Hatton

Affiliations

Soon will be listed here.

Abstract

The lubrication regime displayed by human salivas (parotid and submandibular-sublingual), purified salivary molecules (the mucins MG1 and MG2 and alpha-amylases), and selected artificial salivas (Oracare D, Saliva Substitute, and Orthana) was assessed in vitro using a friction-testing device. Thin-film (boundary) lubrication was observed for all of the salivary samples and two of the artificial salivas examined. Oracare D, a glycerol-based artificial saliva, was the exception since it lubricated by a thick-film (hydrodynamic) regime. On a molar basis, the best lubricants of the purified salivary molecules were MG1 greater than MG2 approximately nonglycosylated alpha-amylases approximately glycosylated alpha-amylases.

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