Clinical Observations and Occurrence of Complications Following Heavy Silicone Oil Surgery

Overview

Journal Biomed Res Int

Publisher Wiley

Specialties Biomedical Engineering
Biotechnology
General Medicine

Date 2014 May 16

PMID 24829913

Citations 1

Authors

Hendrik Schwarzer

Babac Mazinani

Niklas Plange

Matthias Fuest

Peter Walter

Gernot Roessler

Affiliations

Soon will be listed here.

Abstract

Purpose: To demonstrate development and complications in heavy silicone oil (HSO) surgery in 100 eyes following primary vitreoretinal surgery.

Methods: 100 eyes were included in this retrospective study that underwent vitreoretinal surgery using HSO as endotamponade. Indication diagnoses were retinal detachments (n = 76), complicated macular holes (MH) (n = 20), and others (n = 4). HSO removal was performed after a mean period of 20.2 ± 19.0 weeks. In 18 eyes with poor functional prognosis the silicone oil remained permanently for stabilisation. Overall follow-up time was 35.9 ± 51.8 weeks.

Results: The mean IOP before HSO surgery was 13.3 ± 5.6 mmHg and raised to an average maximum of 23.3 ± 8.5 mmHg postoperatively and decreased to 13.7 ± 7.2 mmHg after removal. Secondary IOP raise due to emulsification of the silicone oil endotamponade was seen in 29 eyes after 7.8 ± 4.5 weeks. Other complications being observed with HSO installed were persistent corneal erosion (n = 3) and prolonged anterior chamber inflammation (n = 29). In 13 eyes recurrent retinal detachments occurred during followup.

Conclusions: According to our analysis HSO surgery might deliver satisfying results in complicated cases of ophthalmological surgery. However, potential complications should always be taken into account when making the decision if to use and when to remove HSO in complicated retinal surgery.

Citing Articles

An analysis of heavy silicone oil treatment for inferior proliferative vitreoretinopathy.

Hammer M, Ie A, Eibenberger K, Auffarth G, Xue K BMC Ophthalmol. 2025; 25(1):38.

PMID: 39844136 PMC: 11756122. DOI: 10.1186/s12886-024-03834-7.

Risk factors for epiretinal membrane in eyes with primary rhegmatogenous retinal detachment that received silicone oil tamponade.

Pan Q, Gao Z, Hu X, Wu Q, Zheng J, Zhang Z Br J Ophthalmol. 2022; 107(6):856-861.

PMID: 35184034 PMC: 10314004. DOI: 10.1136/bjophthalmol-2021-320121.

References

Romano M, Vallejo-Garcia J, Parmeggiani F, Romano V, Vito R, Vinciguerra P . Interaction between perfluorcarbon liquid and heavy silicone oil: risk factor for "sticky oil" formation. Curr Eye Res. 2012; 37(7):563-6. DOI: 10.3109/02713683.2012.669511. View

Majid M, Hussin H, Biswas S, Haynes R, Mayer E, Dick A . Emulsification of Densiron-68 used in inferior retinal detachment surgery. Eye (Lond). 2007; 22(1):152-7. DOI: 10.1038/sj.eye.6702784. View

Wolf S, Schon V, Meier P, Wiedemann P . Silicone oil-RMN3 mixture ("heavy silicone oil") as internal tamponade for complicated retinal detachment. Retina. 2003; 23(3):335-42. DOI: 10.1097/00006982-200306000-00008. View

Herbrig E, Sandner D, Engelmann K . Anatomical and functional results of endotamponade with heavy silicone oil - Densiron 68 - in complicated retinal detachment. Ophthalmic Res. 2007; 39(4):198-206. DOI: 10.1159/000104681. View

Heimann H, Stappler T, Wong D . Heavy tamponade 1: a review of indications, use, and complications. Eye (Lond). 2008; 22(10):1342-59. DOI: 10.1038/eye.2008.61. View

Muether P, Hoerster R, Kirchhof B, Fauser S . Course of intraocular pressure after vitreoretinal surgery: is early postoperative intraocular pressure elevation predictable?. Retina. 2011; 31(8):1545-52. DOI: 10.1097/IAE.0b013e31820f4b05. View

Wong D, Kumar I, Quah S, Ali H, Valldeperas X, Valdeperas X . Comparison of postoperative intraocular pressure in patients with Densiron-68 vs conventional silicone oil: a case-control study. Eye (Lond). 2007; 23(1):190-4. DOI: 10.1038/sj.eye.6703055. View

Duan A, She H, Qi Y . Complications after heavy silicone oil tamponade in complicated retinal detachment. Retina. 2010; 31(3):547-52. DOI: 10.1097/IAE.0b013e3181eef2fd. View

Theelen T, Tilanus M, Klevering B . Intraocular inflammation following endotamponade with high-density silicone oil. Graefes Arch Clin Exp Ophthalmol. 2004; 242(7):617-20. DOI: 10.1007/s00417-004-0898-7. View

10.

Lappas A, Kirchhof B, Konen W . [Effects of the long-term tamponade with Densiron on the lens]. Klin Monbl Augenheilkd. 2007; 224(5):434-7. DOI: 10.1055/s-2007-963150. View

11.

Levasseur S, Schendel S, Machuck R, Dhanda D . High-density silicone oil Densiron-68 as an intraocular tamponade for primary inferior retinal detachments. Retina. 2012; 33(3):627-33. DOI: 10.1097/IAE.0b013e3182725d49. View

12.

Cheung B, Lai T, Yuen C, Lai W, Tsang C, Lam D . Results of high-density silicone oil as a tamponade agent in macular hole retinal detachment in patients with high myopia. Br J Ophthalmol. 2007; 91(6):719-21. PMC: 1955589. DOI: 10.1136/bjo.2006.111526. View

13.

Stappler T, Heimann H, Gibran S, Groenewald C, Pearce I, Wong D . [Densiron-68 heavy silicone oil in cases of PVR. Anatomic and functional outcomes]. Ophthalmologe. 2008; 106(4):320-6. DOI: 10.1007/s00347-008-1798-8. View

14.

Han D, Lewis H, Lambrou Jr F, Mieler W, Hartz A . Mechanisms of intraocular pressure elevation after pars plana vitrectomy. Ophthalmology. 1989; 96(9):1357-62. DOI: 10.1016/s0161-6420(89)32715-1. View

15.

Rizzo S, Genovesi-Ebert F, Belting C, Vento A, Cresti F . A pilot study on the use of silicone oil-RMN3 as heavier-than-water endotamponade agent. Graefes Arch Clin Exp Ophthalmol. 2005; 243(11):1153-7. DOI: 10.1007/s00417-005-0015-6. View

16.

Sandner D, Engelmann K . First experiences with high-density silicone oil (Densiron) as an intraocular tamponade in complex retinal detachment. Graefes Arch Clin Exp Ophthalmol. 2005; 244(5):609-19. DOI: 10.1007/s00417-005-0110-8. View

17.

Auriol S, Pagot-Mathis V, Mahieu L, Lemoine C, Mathis A . Efficacy and safety of heavy silicone oil Densiron 68 in the treatment of complicated retinal detachment with large inferior retinectomy. Graefes Arch Clin Exp Ophthalmol. 2008; 246(10):1383-9. DOI: 10.1007/s00417-008-0876-6. View

18.

Li W, Zheng J, Zheng Q, Wu R, Wang X, Xu M . Clinical complications of Densiron 68 intraocular tamponade for complicated retinal detachment. Eye (Lond). 2009; 24(1):21-8. DOI: 10.1038/eye.2009.57. View

19.

Tognetto D, Minutola D, Sanguinetti G, Ravalico G . Anatomical and functional outcomes after heavy silicone oil tamponade in vitreoretinal surgery for complicated retinal detachment: a pilot study. Ophthalmology. 2005; 112(9):1574. DOI: 10.1016/j.ophtha.2005.04.013. View

20.

Honavar S, Goyal M, Majji A, Sen P, Naduvilath T, Dandona L . Glaucoma after pars plana vitrectomy and silicone oil injection for complicated retinal detachments. Ophthalmology. 1999; 106(1):169-76; discussion 177. DOI: 10.1016/S0161-6420(99)90017-9. View