Small G Proteins Dexras1 and RHES and Their Role in Pathophysiological Processes

Overview

Journal Int J Cell Biol

Publisher Wiley

Specialty Cell Biology

Date 2014 May 13

PMID 24817889

Citations 8

Authors

Ashish Thapliyal

Rashmi Verma

Navin Kumar

Affiliations

Soon will be listed here.

Abstract

Dexras1 and RHES, monomeric G proteins, are members of small GTPase family that are involved in modulation of pathophysiological processes. Dexras1 and RHES levels are modulated by hormones and Dexras1 expression undergoes circadian fluctuations. Both these GTPases are capable of modulating calcium ion channels which in turn can potentially modulate neurosecretion/hormonal release. These two GTPases have been reported to prevent the aberrant cell growth and induce apoptosis in cell lines. Present review focuses on role of these two monomeric GTPases and summarizes their role in pathophysiological processes.

Citing Articles

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