Transcatheter Aortic Valve Implantation-induced Left Bundle Branch Block: Causes and Consequences

Overview

Journal J Cardiovasc Transl Res

Publisher Springer

Specialty Cardiology & Vascular Diseases

Date 2014 May 8

PMID 24800873

Citations 8

Authors

Thomas T Poels

Patrick Houthuizen

Leen A F M van Garsse

Jos G Maessen

Peter de Jaegere

Frits W Prinzen

Affiliations

Soon will be listed here.

Abstract

Transcatheter aortic valve implantation (TAVI) is an alternative treatment option for patients with severe aortic valve stenosis who do not qualify for surgical aortic valve replacement (AVR). Besides its proven clinical benefits, one of the complications of TAVI is the creation of conduction abnormalities, like left bundle branch block (LBBB). New LBBB occurs between 7 and 65% of cases, numbers that differ considerably between devices. In this review, we discuss the possible causes and the clinical significance of TAVI-induced LBBB. Several device- and procedural-related factors seem responsible for the development of LBBB, of which depth of implantation and balloon-annulus diameter ratio are the most important ones. TAVI-induced LBBB negatively affects cardiac function and hospitalization, but its impact on mortality is subject of debate. Future research and registries should implement strict diagnostic criteria for LBBB together with recording of its timing and persistence.

Citing Articles

Impact of New-Onset Conduction Disturbances following Transcatheter Aortic Valve Replacement on Outcomes: A Single-Center Study.

See C, Wang Y, Huang H, Parise H, Yang Y, Tirziu D J Interv Cardiol. 2023; 2023:5390338.

PMID: 37292113 PMC: 10247319. DOI: 10.1155/2023/5390338.

Occurrence and Persistency of Conduction Disturbances during Transcatheter Aortic Valve Implantation.

Poels T, Engels E, Kats S, Veenstra L, van Ommen V, Vernooy K Medicina (Kaunas). 2021; 57(7).

PMID: 34356976 PMC: 8303948. DOI: 10.3390/medicina57070695.

Effective Distance between Aortic Valve and Conduction System Is an Independent Predictor of Persistent Left Bundle Branch Block during Transcatheter Aortic Valve Implantation.

Poels T, Stassen R, Kats S, Veenstra L, van Ommen V, Kietselaer B Medicina (Kaunas). 2021; 57(5).

PMID: 34064932 PMC: 8150689. DOI: 10.3390/medicina57050476.

The Vectorcardiogram and the Main Dromotropic Disturbances.

Perez-Riera A, Barbosa-Barros R, Daminello-Raimundo R, de Abreu L, Nikus K Curr Cardiol Rev. 2020; 17(1):50-59.

PMID: 32778036 PMC: 8142362. DOI: 10.2174/1573403X16666200810105504.

Left bundle branch block: Epidemiology, etiology, anatomic features, electrovectorcardiography, and classification proposal.

Perez-Riera A, Barbosa-Barros R, de Rezende Barbosa M, Daminello-Raimundo R, de Abreu L, Nikus K Ann Noninvasive Electrocardiol. 2018; 24(2):e12572.

PMID: 29932265 PMC: 6931474. DOI: 10.1111/anec.12572.

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