Brain Activation During Phonological and Semantic Processing of Chinese Characters in Deaf Signers

Overview

Journal Front Hum Neurosci

Specialty Neurology

Date 2014 May 6

PMID 24795593

Citations 4

Authors

Yanyan Li

Danling Peng

Li Liu

James R Booth

Guosheng Ding

Affiliations

Soon will be listed here.

Abstract

Previous studies found altered brain function in deaf individuals reading alphabetic orthographies. However, it is not known whether similar alterations of brain function are characteristic of non-alphabetic writing systems and whether alterations are specific to certain kinds of lexical tasks. Here we examined differences in brain activation between Chinese congenitally deaf individuals (CD) and hearing controls (HC) during character reading tasks requiring phonological and semantic judgments. For both tasks, we found that CD showed less activation than HC in left inferior frontal gyrus, but greater activation in several right hemisphere regions including inferior frontal gyrus, angular gyrus, and inferior temporal gyrus. Although many group differences were similar across tasks, greater activation in right middle frontal gyrus was more pronounced for the rhyming compared to the meaning task. Finally, within the deaf individuals better performance on the rhyming task was associated with less activation in right inferior parietal lobule and angular gyrus. Our results in Chinese CD are broadly consistent with previous studies in alphabetic languages suggesting greater engagement of inferior frontal gyrus and inferior parietal cortex for reading that is largely independent of task, with the exception of right middle frontal gyrus for phonological processing. The brain behavior correlations potentially indicate that CD that more efficiently use the right hemisphere are better readers.

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References

Eden G, Jones K, Cappell K, Gareau L, Wood F, Zeffiro T . Neural changes following remediation in adult developmental dyslexia. Neuron. 2004; 44(3):411-22. DOI: 10.1016/j.neuron.2004.10.019. View

Vinckier F, Dehaene S, Jobert A, Dubus J, Sigman M, Cohen L . Hierarchical coding of letter strings in the ventral stream: dissecting the inner organization of the visual word-form system. Neuron. 2007; 55(1):143-56. DOI: 10.1016/j.neuron.2007.05.031. View

Poldrack R, Wagner A, Prull M, Desmond J, Glover G, Gabrieli J . Functional specialization for semantic and phonological processing in the left inferior prefrontal cortex. Neuroimage. 1999; 10(1):15-35. DOI: 10.1006/nimg.1999.0441. View

Hanson V, Fowler C . Phonological coding in word reading: evidence from hearing and deaf readers. Mem Cognit. 1987; 15(3):199-207. DOI: 10.3758/bf03197717. View

Sterne A, Goswami U . Phonological awareness of syllables, rhymes, and phonemes in deaf children. J Child Psychol Psychiatry. 2000; 41(5):609-25. DOI: 10.1111/1469-7610.00648. View

Booth J, Lu D, Burman D, Chou T, Jin Z, Peng D . Specialization of phonological and semantic processing in Chinese word reading. Brain Res. 2006; 1071(1):197-207. PMC: 2626184. DOI: 10.1016/j.brainres.2005.11.097. View

Bitan T, Cheon J, Lu D, Burman D, Gitelman D, Mesulam M . Developmental changes in activation and effective connectivity in phonological processing. Neuroimage. 2007; 38(3):564-75. PMC: 2638503. DOI: 10.1016/j.neuroimage.2007.07.048. View

Turkeltaub P, Gareau L, Lynn Flowers D, Zeffiro T, Eden G . Development of neural mechanisms for reading. Nat Neurosci. 2003; 6(7):767-73. DOI: 10.1038/nn1065. View

Morford J, Wilkinson E, Villwock A, Pinar P, Kroll J . When deaf signers read English: do written words activate their sign translations?. Cognition. 2010; 118(2):286-92. PMC: 3034361. DOI: 10.1016/j.cognition.2010.11.006. View

10.

Chou T, Chen C, Wu M, Booth J . The role of inferior frontal gyrus and inferior parietal lobule in semantic processing of Chinese characters. Exp Brain Res. 2009; 198(4):465-75. PMC: 3277261. DOI: 10.1007/s00221-009-1942-y. View

11.

Price C, Gorno-Tempini M, Graham K, Biggio N, Mechelli A, Patterson K . Normal and pathological reading: converging data from lesion and imaging studies. Neuroimage. 2003; 20 Suppl 1:S30-41. DOI: 10.1016/j.neuroimage.2003.09.012. View

12.

Ross P, Pergament L, ANISFELD M . Cerebral lateralization of deaf and hearing individuals for linguistic comparison judgments. Brain Lang. 1979; 8(1):69-80. DOI: 10.1016/0093-934x(79)90041-5. View

13.

Emmorey K, Damasio H, McCullough S, Grabowski T, Ponto L, Hichwa R . Neural systems underlying spatial language in American Sign Language. Neuroimage. 2002; 17(2):812-24. View

14.

Geers A . Predictors of reading skill development in children with early cochlear implantation. Ear Hear. 2003; 24(1 Suppl):59S-68S. DOI: 10.1097/01.AUD.0000051690.43989.5D. View

15.

Tan L, Spinks J, Eden G, Perfetti C, Siok W . Reading depends on writing, in Chinese. Proc Natl Acad Sci U S A. 2005; 102(24):8781-5. PMC: 1150863. DOI: 10.1073/pnas.0503523102. View

16.

Booth J, Burman D, Meyer J, Gitelman D, Parrish T, Marsel Mesulam M . Development of brain mechanisms for processing orthographic and phonologic representations. J Cogn Neurosci. 2004; 16(7):1234-49. PMC: 1382289. DOI: 10.1162/0898929041920496. View

17.

Friederici A, Opitz B, von Cramon D . Segregating semantic and syntactic aspects of processing in the human brain: an fMRI investigation of different word types. Cereb Cortex. 2000; 10(7):698-705. DOI: 10.1093/cercor/10.7.698. View

18.

Green W, SHEPHERD D . The semantic structure in deaf children. J Commun Disord. 1975; 8(4):357-65. DOI: 10.1016/0021-9924(75)90037-4. View

19.

Capek C, Waters D, Woll B, MacSweeney M, Brammer M, McGuire P . Hand and mouth: cortical correlates of lexical processing in British Sign Language and speechreading English. J Cogn Neurosci. 2008; 20(7):1220-34. PMC: 3370423. DOI: 10.1162/jocn.2008.20084. View

20.

Neville H, Bavelier D, Corina D, Rauschecker J, Karni A, Lalwani A . Cerebral organization for language in deaf and hearing subjects: biological constraints and effects of experience. Proc Natl Acad Sci U S A. 1998; 95(3):922-9. PMC: 33817. DOI: 10.1073/pnas.95.3.922. View