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Development of an Open Source Software Module for Enhanced Visualization During MR-guided Interstitial Gynecologic Brachytherapy

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Journal Springerplus
Date 2014 May 3
PMID 24790816
Citations 1
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Abstract

In 2010, gynecologic malignancies were the 4th leading cause of death in U.S. women and for patients with extensive primary or recurrent disease, treatment with interstitial brachytherapy may be an option. However, brachytherapy requires precise insertion of hollow catheters with introducers into the tumor in order to eradicate the cancer. In this study, a software solution to assist interstitial gynecologic brachytherapy has been investigated and the software has been realized as an own module under (3D) Slicer, which is a free open source software platform for (translational) biomedical research. The developed research module allows on-time processing of intra-operative magnetic resonance imaging (iMRI) data over a direct DICOM connection to a MR scanner. Afterwards follows a multi-stage registration of CAD models of the medical brachytherapy devices (template, obturator) to the patient's MR images, enabling the virtual placement of interstitial needles to assist the physician during the intervention.

Citing Articles

MR diffusion-weighted imaging-based subcutaneous tumour volumetry in a xenografted nude mouse model using 3D Slicer: an accurate and repeatable method.

Ma Z, Chen X, Huang Y, He L, Liang C, Liang C Sci Rep. 2015; 5:15653.

PMID: 26489359 PMC: 4614907. DOI: 10.1038/srep15653.

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