Secondary Acute Lymphoblastic Leukemia After Hodgkin's Lymphoma or a Coincidental Association of Two Hematological Malignancies?

Overview

Journal Maedica (Bucur)

Specialty General Medicine

Date 2014 May 3

PMID 24790671

Authors

Mihaela Tevet

Cornel Dragan

Carmen Saguna

Doina Barbu

Anca Roxana Lupu

Affiliations

Soon will be listed here.

Abstract

Abstract: Secondary acute lymphoblastic leukaemia (sALL), defined as acute lymphoblastic leukaemia following another malignancy, irrespective of previous treatment, is a rare disease, and its biological characteristics have not been accurately described. We report the case of a 24-year old patient followed for Hodgkin's lymphoma at our clinic, who develops and is diagnosed, less than a year after obtaining complete remission, as having pro-B acute lymphoblastic leukaemia This case has been a real diagnostic and treatment challenge, as sALL following another haematological malignancy is quite rare.

Conclusion: It is necessary to better identify the prognostic factors of haematological malignancies in order to prevent the appearance of sALL.

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