Psychiatric Problems in Children and Adolescents with Sickle Cell Disease, Based on Parent and Teacher Reports

Overview

Journal Turk J Haematol

Specialty Hematology

Date 2014 Apr 19

PMID 24744670

Citations 3

Authors

Ozalp Ekinci

Tanju Celik

Sule Unal

Cahit Ozer

Affiliations

Soon will be listed here.

Abstract

Objective: This study aimed to investigate the occurrence of psychiatric problems in children and adolescents withsickle cell disease (SCD).

Material And Methods: The Child Behavior Checklist for ages 4-18 years (CBCL/4-18), Conners' Parent RatingScale (CPRS), Conners' Teacher Rating Scale (CTRS-R), and The Turgay DSM-IV Based Child and Adolescent BehaviorDisorders Screening and Rating Scale, clinician and parent forms (T-DSM-IV-S) were given to the caregivers and teachersof 31 children with SCD aged between 7-18 years and the caregivers and teachers of 34 age matched controls with irondeficiencyanemia.

Results: The SCD patients had higher scores on all 4 of scales. Among the subscales, internalizing problems, andattention problems were more prominent in the SCD patients.

Conclusion: Children and adolescents with SCD appear to have an increased risk for psychiatric problems. Regularpsychological evaluation and referral to child and adolescent psychiatry clinics may facilitate timely diagnosis andeffective treatment of at-risk children and adolescents.

Citing Articles

Fatigue, Stress Appraisal, and Emotional Functioning Among Youth With Sickle Cell Disease: A Daily Diary Study.

Reinman L, Schatz J, Johnston J, Bills S J Pediatr Psychol. 2023; 48(6):562-571.

PMID: 37167536 PMC: 10321392. DOI: 10.1093/jpepsy/jsad019.

Predictors and Correlates of Fatigue in Sickle Cell Disease Patients.

Ahmadi M, Poormansouri S, Beiranvand S, Sedighie L Int J Hematol Oncol Stem Cell Res. 2018; 12(1):69-76.

PMID: 29951181 PMC: 6018252.

Comprehensive neuropsychological evaluation of children and adolescents with sickle cell anemia: a hospital-based sample.

Nunes S, Argollo N, Mota M, Vieira C, de Sena E Rev Bras Hematol Hemoter. 2017; 39(1):32-39.

PMID: 28270343 PMC: 5339374. DOI: 10.1016/j.bjhh.2016.09.004.

References

Palermo T, Schwartz L, Drotar D, McGowan K . Parental report of health-related quality of life in children with sickle cell disease. J Behav Med. 2002; 25(3):269-83. DOI: 10.1023/a:1015332828213. View

Jerrell J, Tripathi A, McIntyre R . Prevalence and treatment of depression in children and adolescents with sickle cell disease: a retrospective cohort study. Prim Care Companion CNS Disord. 2011; 13(2). PMC: 3184596. DOI: 10.4088/PCC.10m01063. View

Benton T, Boyd R, Ifeagwu J, Feldtmose E, Smith-Whitley K . Psychiatric diagnosis in adolescents with sickle cell disease: a preliminary report. Curr Psychiatry Rep. 2011; 13(2):111-5. DOI: 10.1007/s11920-011-0177-3. View

Goyette C, Conners C, Ulrich R . Normative data on revised Conners Parent and Teacher Rating Scales. J Abnorm Child Psychol. 1978; 6(2):221-36. DOI: 10.1007/BF00919127. View

Burke P, Elliott M . Depression in pediatric chronic illness. A diathesis-stress model. Psychosomatics. 1999; 40(1):5-17. DOI: 10.1016/S0033-3182(99)71266-1. View

Brown R, Kaslow N, Doepke K, Buchanan I, ECKMAN J, Baldwin K . Psychosocial and family functioning in children with sickle cell syndrome and their mothers. J Am Acad Child Adolesc Psychiatry. 1993; 32(3):545-53. DOI: 10.1097/00004583-199305000-00009. View

Hijmans C, Grootenhuis M, Oosterlaan J, Last B, Heijboer H, Peters M . Behavioral and emotional problems in children with sickle cell disease and healthy siblings: Multiple informants, multiple measures. Pediatr Blood Cancer. 2009; 53(7):1277-83. DOI: 10.1002/pbc.22257. View

Craft S, Schatz J, Glauser T, Lee B, DeBaun M . Neuropsychologic effects of stroke in children with sickle cell anemia. J Pediatr. 1993; 123(5):712-7. DOI: 10.1016/s0022-3476(05)80844-3. View

Berkelhammer L, Williamson A, Sanford S, Dirksen C, Sharp W, Margulies A . Neurocognitive sequelae of pediatric sickle cell disease: a review of the literature. Child Neuropsychol. 2007; 13(2):120-31. DOI: 10.1080/09297040600800956. View

10.

Brandling-Bennett E, White D, Armstrong M, Christ S, DeBaun M . Patterns of verbal long-term and working memory performance reveal deficits in strategic processing in children with frontal infarcts related to sickle cell disease. Dev Neuropsychol. 2003; 24(1):423-34. DOI: 10.1207/S15326942DN2401_01. View

11.

Brown R, DAVIS P, Lambert R, Hsu L, Hopkins K, ECKMAN J . Neurocognitive functioning and magnetic resonance imaging in children with sickle cell disease. J Pediatr Psychol. 2000; 25(7):503-13. DOI: 10.1093/jpepsy/25.7.503. View

12.

Nabors N, Freymuth A . Attention deficits in children with sickle cell disease. Percept Mot Skills. 2002; 95(1):57-67. DOI: 10.2466/pms.2002.95.1.57. View

13.

Curuk M, Zeren F, Genc A, Ozavci-Aygun S, Kilinc Y, Aksoy K . Prenatal diagnosis of sickle cell anemia and beta-thalassemia in southern Turkey. Hemoglobin. 2008; 32(6):525-30. DOI: 10.1080/03630260802508269. View

14.

Midence K, Fuggle P, Davies S . Psychosocial aspects of sickle cell disease (SCD) in childhood and adolescence: a review. Br J Clin Psychol. 1993; 32(3):271-80. DOI: 10.1111/j.2044-8260.1993.tb01057.x. View

15.

Benton T, Ifeagwu J, Smith-Whitley K . Anxiety and depression in children and adolescents with sickle cell disease. Curr Psychiatry Rep. 2007; 9(2):114-21. DOI: 10.1007/s11920-007-0080-0. View

16.

Alao A, Dewan M, Jindal S, Effron M . Psychopathology in sickle cell disease. West Afr J Med. 2004; 22(4):334-7. DOI: 10.4314/wajm.v22i4.28059. View

17.

Trzepacz A, Vannatta K, Gerhardt C, Ramey C, Noll R . Emotional, Social, and Behavioral Functioning of Children With Sickle Cell Disease and Comparison Peers. J Pediatr Hematol Oncol. 2004; 26(10):642-648. DOI: 10.1097/01.mph.0000139456.12036.8d. View

18.

Dereboy C, Senol S, Sener S, Dereboy F . [Validation of the Turkish versions of the short-form Conners' teacher and parent rating scales]. Turk Psikiyatri Derg. 2007; 18(1):48-58. View

19.

Tunde-Ayinmode M, Adelekan M . Psychosocial impact of sickle cell disease in children seen at University of Ilorin Teaching Hospital, Ilorin, Nigeria. East Afr Med J. 2005; 82(2):73-8. DOI: 10.4314/eamj.v82i2.9258. View

20.

Dale J, Cochran C, Roy L, Jernigan E, Buchanan G . Health-related quality of life in children and adolescents with sickle cell disease. J Pediatr Health Care. 2011; 25(4):208-15. PMC: 3124665. DOI: 10.1016/j.pedhc.2009.12.006. View