Can Cycles of Chills and Fever Resolve Bipolar Disorder Mania?

Overview

Journal BMJ Case Rep

Specialty General Medicine

Date 2014 Apr 15

PMID 24728894

Authors

Audun Setsaas

Arne Einar Vaaler

Affiliations

Soon will be listed here.

Abstract

Treatment resistance is common in populations of patients with bipolar disorder stressing the need for new therapeutic strategies. Favourable effects of fever on mental disease have been noted throughout history. Today there is increasing evidence that immunological processes are involved in the pathophysiology of mental disorders. We present a case in which a patient with treatment resistant bipolar disorder mania seemingly recovered as a result of recurrent fever. This indicates that artificial fever might become a last resort therapy for treatment resistant mania.

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