» Articles » PMID: 24713718

The Lesch Alcoholism Typology - Psychiatric and Psychosocial Treatment Approaches

Overview
Specialty Gastroenterology
Date 2014 Apr 10
PMID 24713718
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

In the past three decades, researchers have been attempting to replace the obsolete concept of homogeneity of alcohol dependence, by classifying these patients into specific heterogeneous subtypes. Based on 30 years of experience and research, the Lesch Typology has proved to be very useful in clinical daily routine. The aim of the Lesch Typology is to provide targeted subtype-specific treatments to patients, thereby increasing their probability of long-term abstinence and hence improving their prognosis. The Lesch Typology is based on data from a longitudinal prospective study (with follow ups even 19 years later) on alcohol dependent patients (n=436). By observing the long term development of these patients, four distinct courses could be identified. In the meantime, a computerized version of the Lesch Typology had been created and translated into many languages, and is currently being employed in numerous psychiatric institutions while assisting clinicians in quickly determining a patient's subtype (www.lat-online.at). Based on the patients' drinking patterns and origin of substance craving, hence according to the Lesch Typology, four subtypes of alcohol dependent patients can be distinguished: 1. the "allergy model" (craving caused by alcohol); 2. the "conflict resolution and anxiety model" (craving caused by stress); 3. the "depressive model" (craving caused by mood); and 4. the "conditioning model" (craving caused by compulsion). Pharmacological treatments are not always the most effective way of preventing relapses in alcohol dependent patients. Many times, a combination with psychosocial as well as psychotherapeutic approaches is necessary and essential for helping patients to stay sober. Depending on the patient's Lesch Type, certain therapeutic approaches are more appropriate and subsequently lead to better results and higher chances of lasting abstinence.

Citing Articles

A scoping review of electroencephalographic (EEG) markers for tracking neurophysiological changes and predicting outcomes in substance use disorder treatment.

Bel-Bahar T, Khan A, Shaik R, Parvaz M Front Hum Neurosci. 2022; 16:995534.

PMID: 36325430 PMC: 9619053. DOI: 10.3389/fnhum.2022.995534.


The Molecular Basis of Alcohol Use Disorder (AUD). Genetics, Epigenetics, and Nutrition in AUD: An Amazing Triangle.

Siomek-Gorecka A, Dlugosz A, Czarnecki D Int J Mol Sci. 2021; 22(8).

PMID: 33924016 PMC: 8072802. DOI: 10.3390/ijms22084262.


First and Subsequent Lifetime Alcoholism and Mental Disorders in Suicide Victims With Reference to a Community Sample-the Lundby Study 1947-1997.

Holmstrand C, Bogren M, Mattisson C, Bradvik L Front Psychiatry. 2018; 9:173.

PMID: 29773997 PMC: 5943570. DOI: 10.3389/fpsyt.2018.00173.


Belief about Nicotine Modulates Subjective Craving and Insula Activity in Deprived Smokers.

Gu X, Lohrenz T, Salas R, Baldwin P, Soltani A, Kirk U Front Psychiatry. 2016; 7:126.

PMID: 27468271 PMC: 4942468. DOI: 10.3389/fpsyt.2016.00126.


New diagnostic criteria for alcohol use disorders and novel treatment approaches - 2014 update.

Tyburski E, Sokolowski A, Samochowiec J, Samochowiec A Arch Med Sci. 2015; 10(6):1191-7.

PMID: 25624858 PMC: 4296075. DOI: 10.5114/aoms.2014.47829.


References
1.
Bramer G . International statistical classification of diseases and related health problems. Tenth revision. World Health Stat Q. 1988; 41(1):32-6. View

2.
OMalley S . Opioid antagonists in the treatment of alcohol dependence: clinical efficacy and prevention of relapse. Alcohol Alcohol. 1996; 31 Suppl 1:77-81. View

3.
Lejoyeux M, Solomon J, Ades J . Benzodiazepine treatment for alcohol-dependent patients. Alcohol Alcohol. 1999; 33(6):563-75. DOI: 10.1093/alcalc/33.6.563. View

4.
Witkiewitz K, Hartzler B, Donovan D . Matching motivation enhancement treatment to client motivation: re-examining the Project MATCH motivation matching hypothesis. Addiction. 2010; 105(8):1403-13. PMC: 3157315. DOI: 10.1111/j.1360-0443.2010.02954.x. View

5.
Chick J, Anton R, Checinski K, Croop R, Drummond D, Farmer R . A multicentre, randomized, double-blind, placebo-controlled trial of naltrexone in the treatment of alcohol dependence or abuse. Alcohol Alcohol. 2000; 35(6):587-93. DOI: 10.1093/alcalc/35.6.587. View