Managing Malignant Pericardial Effusion

Overview

Journal West J Med

Specialty General Medicine

Date 1989 Feb 1

PMID 2471362

Citations 5

Authors

A C Buzaid

H S Garewal

B R Greenberg

Affiliations

Soon will be listed here.

Abstract

The involvement of the pericardium by metastatic tumors is not uncommon, particularly in patients with lung cancer, breast cancer, lymphomas, leukemias, and melanomas. There are five therapeutic modalities for the treatment of malignant pericardial effusion, including pericardiocentesis, pericardial sclerosis, systemic chemotherapy, radiotherapy, and surgical treatment. The optimal treatment selection is dependent principally on a patient's life expectancy; responsiveness of the tumor to chemotherapy, irradiation, or both; and whether or not cardiac tamponade is present at diagnosis. The overall prognosis of patients with malignant pericardial effusion is primarily influenced by the extent and histologic features of the underlying cancer. Although this condition is usually incurable, a reasonable period of useful palliation can be obtained in most patients.

Citing Articles

Would the Addition of Immunotherapy Impact the Prognosis of Patients With Malignant Pericardial Effusion?.

Chiruvella V, Ullah A, Elhelf I, Patel N, Karim N Front Oncol. 2022; 12:871132.

PMID: 35600364 PMC: 9120828. DOI: 10.3389/fonc.2022.871132.

Anaplastic Lymphoma Kinase-Positive Primary Lung Adenocarcinoma Presenting With Pericardial Effusion and Tamponade in a COVID-19 Patient: A Case Report.

Rahman A, Folaranmi O, Chan V, Chaudary A Cureus. 2021; 13(10):e19127.

PMID: 34868767 PMC: 8627680. DOI: 10.7759/cureus.19127.

Clinical experience with pericardiocentesis and extended drainage in a population with a high prevalence of HIV.

Louw V, Reuter H, Smedema J, Katjitae I, Burgess L, Doubell A Neth Heart J. 2015; 10(10):399-406.

PMID: 25696035 PMC: 2499794.

Case report: cardiac tamponade resembling an acute myocardial infarction as the initial manifestation of metastatic pericardial adenocarcinoma.

Scheinin S, Sosa-Herrera J Methodist Debakey Cardiovasc J. 2014; 10(2):124-8.

PMID: 25114766 PMC: 4117332. DOI: 10.14797/mdcj-10-2-124.

Diagnosis and management of cardiac tamponade in the era of echocardiography.

Tsang T, Oh J, Seward J Clin Cardiol. 1999; 22(7):446-52.

PMID: 10410287 PMC: 6656203. DOI: 10.1002/clc.4960220703.

References

Ghosh S, Larrieu A, ABLAZA S, Grana V . Clinical experience with subxyphoid pericardial decompression. Int Surg. 1985; 70(1):5-7. View

Berman K, Fielding L, Richi A . Diagnosis and treatment of malignant pericardial effusion: the subxiphoid approach. Conn Med. 1984; 48(11):701-2. View

Lopez J, Delgado J, Tovar E, Gonzalez A . Massive pericardial effusion produced by extracardiac malignant neoplasms. Arch Intern Med. 1983; 143(9):1815-6. DOI: 10.1001/archinte.1983.00350090197038. View

Sulkes A, Weshler Z, Kopolovic Y . Pericardial effusion as first evidence of malignancy in bronchogenic carcinoma. J Surg Oncol. 1982; 20(2):71-4. DOI: 10.1002/jso.2930200202. View

Guberman B, FOWLER N, Engel P, Gueron M, Allen J . Cardiac tamponade in medical patients. Circulation. 1981; 64(3):633-40. DOI: 10.1161/01.cir.64.3.633. View

GREGORY J, McMurtrey M, Mountain C . A surgical approach to the treatment of pericardial effusion in cancer patients. Am J Clin Oncol. 1985; 8(4):319-23. DOI: 10.1097/00000421-198508000-00009. View

Alcan K, Zabetakis P, Marino N, Franzone A, Michelis M, BRUNO M . Management of acute cardiac tamponade by subxiphoid pericardiotomy. JAMA. 1982; 247(8):1143-8. View

Agner R, Gallis H . Pericarditis: differential diagnostic considerations. Arch Intern Med. 1979; 139(4):407-12. DOI: 10.1001/archinte.139.4.407. View

Little A, Kremser P, Wade J, Levett J, DeMeester T, SKINNER D . Operation for diagnosis and treatment of pericardial effusions. Surgery. 1984; 96(4):738-44. View

10.

Reyes C, Strinden C, Banerji M . The role of cytology in neoplastic cardiac tamponade. Acta Cytol. 1982; 26(3):299-302. View

11.

Smith F, Lane M, HUDGINS P . Conservative management of malignant pericardial effusion. Cancer. 1974; 33(1):47-57. DOI: 10.1002/1097-0142(197401)33:1<47::aid-cncr2820330110>3.0.co;2-8. View

12.

Johnson M, SOULEN R . Echocardiography of cardiac metastases. AJR Am J Roentgenol. 1983; 141(4):677-81. DOI: 10.2214/ajr.141.4.677. View

13.

COHEN G, PERRY T, Evans J . Neoplastic invasion of the heart and pericardium. Ann Intern Med. 1955; 42(6):1238-45. DOI: 10.7326/0003-4819-42-6-1238. View

14.

Goldman B, PEARSON F . MALIGNANT PERICARDIAL EFFUSION. REVIEW OF HOSPITAL EXPERIENCE AND REPORT OF A CASE SUCCESSFULLY TREATED BY TALC POUDRAGE. Can J Surg. 1965; 8:157-61. View

15.

Reynolds P, Byrne M . The treatment of malignant pericardial effusion in carcinoma of the breast. Aust N Z J Med. 1977; 7(2):169-71. DOI: 10.1111/j.1445-5994.1977.tb04688.x. View

16.

Primrose W, Clee M, Johnston R . Malignant pericardial effusion managed with Vinblastine. Clin Oncol. 1983; 9(1):67-70. View

17.

Wei J, Taylor G, Achuff S . Recurrent cardiac tamponade and large pericardial effusions: management with an indwelling pericardial catheter. Am J Cardiol. 1978; 42(2):281-2. DOI: 10.1016/0002-9149(78)90911-6. View

18.

Callahan J, Seward J, Nishimura R, Miller Jr F, Reeder G, Shub C . Two-dimensional echocardiographically guided pericardiocentesis: experience in 117 consecutive patients. Am J Cardiol. 1985; 55(4):476-9. DOI: 10.1016/0002-9149(85)90397-2. View

19.

HANCOCK E . Pericardial disease--differential diagnosis and management. Hosp Pract (Off Ed). 1983; 18(4):101-12. DOI: 10.1080/21548331.1983.11702516. View

20.

Clarke D, Cosgrove D . Real-time ultrasound scanning in the planning and guidance of pericardiocentesis. Clin Radiol. 1987; 38(2):119-22. DOI: 10.1016/s0009-9260(87)80005-3. View