» Articles » PMID: 24703346

Comorbidities in Patients with Crystal Diseases and Hyperuricemia

Overview
Publisher Elsevier
Specialty Rheumatology
Date 2014 Apr 8
PMID 24703346
Citations 19
Authors
Affiliations
Soon will be listed here.
Abstract

Crystal arthropathies are among the most common causes of painful inflammatory arthritis. Gout, the most common example, has been associated with cardiovascular and renal disease. In recent years, evidence for these associations and those involving other comorbidities, such as the metabolic syndrome, have emerged, and the importance of asymptomatic hyperuricemia has been established. In this review, an update on evidence, both experimental and clinical, is presented, and associations between hyperuricemia, gout, and several comorbidities are described. Causality regarding calcium pyrophosphate arthropathy and associated comorbidities is also reviewed.

Citing Articles

Asymptomatic hyperuricaemia in chronic kidney disease: mechanisms and clinical implications.

Anders H, Li Q, Steiger S Clin Kidney J. 2023; 16(6):928-938.

PMID: 37261000 PMC: 10229286. DOI: 10.1093/ckj/sfad006.


Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress.

Qiao P, Sun Y, Wang Y, Lin S, An Y, Wang L Antioxidants (Basel). 2023; 12(5).

PMID: 37237889 PMC: 10215166. DOI: 10.3390/antiox12051022.


Synovium to Myocardium: A Case of Calcium Pyrophosphate Dihydrate Crystal Arthritis Associated With Myocardial Infarction.

Raza M, Rana M, Arif M, Akinpelu T, Waheed A Cureus. 2023; 15(2):e34528.

PMID: 36879710 PMC: 9984863. DOI: 10.7759/cureus.34528.


Prevalence and Risk Factors of Hyperuricemia and Gout: A Cross-sectional Survey from 31 Provinces in Mainland China.

Song J, Jin C, Shan Z, Teng W, Li J J Transl Int Med. 2022; 10(2):134-145.

PMID: 35959454 PMC: 9328039. DOI: 10.2478/jtim-2022-0031.


Hyperuricemia Is Associated with Significant Liver Fibrosis in Subjects with Nonalcoholic Fatty Liver Disease, but Not in Subjects without It.

Yen P, Chou Y, Li C, Sun Z, Wu C, Chang Y J Clin Med. 2022; 11(5).

PMID: 35268536 PMC: 8911142. DOI: 10.3390/jcm11051445.


References
1.
Duan W, Ladenheim B, Cutler R, Kruman I, Cadet J, Mattson M . Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease. J Neurochem. 2002; 80(1):101-10. DOI: 10.1046/j.0022-3042.2001.00676.x. View

2.
George J, Carr E, Davies J, Belch J, Struthers A . High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid. Circulation. 2006; 114(23):2508-16. DOI: 10.1161/CIRCULATIONAHA.106.651117. View

3.
Ciancio G, Bortoluzzi A, Govoni M . Epidemiology of gout and chondrocalcinosis. Reumatismo. 2012; 63(4):207-20. DOI: 10.4081/reumatismo.2011.207. View

4.
Sanchez-Lozada L, Tapia E, Jimenez A, Bautista P, Cristobal M, Nepomuceno T . Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats. Am J Physiol Renal Physiol. 2006; 292(1):F423-9. DOI: 10.1152/ajprenal.00124.2006. View

5.
Rho Y, Zhu Y, Choi H . The epidemiology of uric acid and fructose. Semin Nephrol. 2011; 31(5):410-9. PMC: 3197219. DOI: 10.1016/j.semnephrol.2011.08.004. View