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9-1-1: HSCs Respond to Emergency Calls

Overview
Journal Cell Stem Cell
Publisher Cell Press
Specialty Cell Biology
Date 2014 Apr 8
PMID 24702988
Citations 8
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Abstract

In this issue of Cell Stem Cell, Zhao et al. (2014) and Schürch et al. (2014) describe two new stem cell mechanisms underlying protective responses to infection. In response to inflammatory signals, HSPCs and MSCs produce cytokines that stimulate HSC mobilization and differentiation toward innate immune cells at the expense of adaptive immune lineages.

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