Screening for Hepatocellular Carcinoma. Review and Perspective

Overview

Journal West J Med

Specialty General Medicine

Date 1988 Aug 1

PMID 2470205

Citations 2

Authors

J C Ellis

Affiliations

Soon will be listed here.

Abstract

In patients with hepatocellular carcinoma, early diagnosis offers the only hope for resection and cure. Data from Asia, where it is closely associated with viral hepatitis, indicate that serum alpha-fetoprotein assay and abdominal ultrasonography are the most effective and feasible screening tests. These data may not be applicable in America, where most patients at risk for hepatocellular carcinoma have underlying alcoholic cirrhosis. Also, it is unclear whether resecting "curable" lesions prolongs survival, particularly in patients with cirrhosis. Screening trials are indicated to answer these questions. Preventing risk factors, however, especially hepatitis B viral disease, is of paramount importance throughout the world.

Citing Articles

Utility of screening for hepatocellular carcinoma among cirrhotics.

Niravath P, Hayes T, Hilsenbeck S Frontline Gastroenterol. 2017; 2(3):182-187.

PMID: 28839606 PMC: 5517217. DOI: 10.1136/fg.2010.003244.

Hepatocellular carcinoma among cirrhotics--utility of screening and surveillance programs--review article.

Oprita R, Diaconescu I, Lupu G, Lupu A, Cristea B, Bratu M J Med Life. 2015; 7(4):477-80.

PMID: 25713606 PMC: 4316122.

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