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Coming Full Circle-from Endless Complexity to Simplicity and Back Again

Overview
Journal Cell
Publisher Cell Press
Specialty Cell Biology
Date 2014 Apr 1
PMID 24679541
Citations 110
Authors
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Abstract

Cell has celebrated the powers of reductionist molecular biology and its major successes for four decades. Those who have participated in cancer research during this period have witnessed wild fluctuations from times where endless inexplicable phenomenology reigned supreme to periods of reductionist triumphalism and, in recent years, to a move back to confronting the endless complexity of this disease.

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