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Portal Hypertensive Gastropathy and Colopathy

Overview
Journal Clin Liver Dis
Specialty Gastroenterology
Date 2014 Apr 1
PMID 24679502
Citations 23
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Abstract

Portal hypertensive gastropathy (PHG) and colopathy (PHC) are considered complications of portal hypertension. Both entities are clinically relevant because they may cause insidious blood loss or even acute massive gastrointestinal hemorrhage. Endoscopic evaluation is necessary for the diagnosis of PHG and PHC. The existence of different endoscopic criteria for PHG and PHC makes consensus difficult and results in a broad range of reported prevalence. Therapy targeted at reduction of portal pressure and mucosal blood flow has been used to treat acute bleeding; nonselective β-blockers are the most frequently used agents. Further studies are needed to clarify the natural history, pathogenesis, and treatment of PHG and PHC.

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References
1.
de Franchis R . Updating consensus in portal hypertension: report of the Baveno III Consensus Workshop on definitions, methodology and therapeutic strategies in portal hypertension. J Hepatol. 2000; 33(5):846-52. DOI: 10.1016/s0168-8278(00)80320-7. View

2.
Lyles T, Elliott A, Rockey D . A risk scoring system to predict in-hospital mortality in patients with cirrhosis presenting with upper gastrointestinal bleeding. J Clin Gastroenterol. 2013; 48(8):712-20. DOI: 10.1097/MCG.0000000000000014. View

3.
Balzer C, Lotterer E, Kleber G, Fleig W . Transjugular intrahepatic portosystemic shunt for bleeding angiodysplasia-like lesions in portal-hypertensive colopathy. Gastroenterology. 1998; 115(1):167-72. DOI: 10.1016/s0016-5085(98)70378-6. View

4.
Misra V, Misra S, Dwivedi M, Singh P, Kumar V . Colonic mucosa in patients with portal hypertension. J Gastroenterol Hepatol. 2003; 18(3):302-8. DOI: 10.1046/j.1440-1746.2003.02980.x. View

5.
Cubillas R, Rockey D . Portal hypertensive gastropathy: a review. Liver Int. 2010; 30(8):1094-102. DOI: 10.1111/j.1478-3231.2010.02286.x. View