Recurrent Aphthous Stomatitis

Overview

Journal Dent Clin North Am

Specialty Dentistry

Date 2014 Mar 25

PMID 24655523

Citations 75

Authors

Sunday O Akintoye

Martin S Greenberg

Affiliations

Soon will be listed here.

Abstract

Recurrent aphthous stomatitis (RAS) is the most common ulcerative disease affecting the oral mucosa. RAS occurs mostly in healthy individuals and has an atypical clinical presentation in immunocompromised individuals. The etiology of RAS is still unknown, but several local, systemic, immunologic, genetic, allergic, nutritional, and microbial factors, as well as immunosuppressive drugs, have been proposed as causative agents. Clinical management of RAS using topical and systemic therapies is based on severity of symptoms and the frequency, size, and number of lesions. The goals of therapy are to decrease pain and ulcer size, promote healing, and decrease the frequency of recurrence.

Citing Articles

Comparative Evaluation of Tacrolimus 0.1% in Orabase and Triamcinolone Acetonide 0.1% in the Management of Recurrent Apthous Stomatitis (RAS) - A Case Control Study.

Manukonda D, Yellarthi P, Pakki S, Bhushan N, Radha G, Chintada V J Pharm Bioallied Sci. 2025; 16(Suppl 4):S4107-S4110.

PMID: 39927004 PMC: 11805023. DOI: 10.4103/jpbs.jpbs_1498_24.

The Possible Impact of Zinc-Enriched Multivitamins on Treatment-Naïve Recurrent Aphthous Stomatitis Patients.

Seo H, Chung K, Kim D J Clin Med. 2025; 14(1.

PMID: 39797342 PMC: 11721099. DOI: 10.3390/jcm14010260.

Wound healing potential of mouth gel containing isopimarane diterpene from rhizomes for treatment of oral stomatitis.

Iadnut A, Sae-Lee T, Tewtrakul S PeerJ. 2024; 12:e18716.

PMID: 39713130 PMC: 11662896. DOI: 10.7717/peerj.18716.

Photobiomodulation in recurrent aphthous stomatitis management using three different laser wavelengths. A randomized clinical trial.

AlHerafi E, Hamadah O, Parker S Lasers Med Sci. 2024; 39(1):285.

PMID: 39557704 DOI: 10.1007/s10103-024-04236-3.

Potential Association Between Vaping and Recurrent Aphthous Stomatitis: A Case Series.

Kotha A, Mandapati S, Rudraraju H Cureus. 2024; 16(9):e70238.

PMID: 39463514 PMC: 11512443. DOI: 10.7759/cureus.70238.

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