» Articles » PMID: 24611212

Schedules of Controlled Substances: Temporary Placement of 10 Synthetic Cathinones into Schedule I. Final Order

Overview
Journal Fed Regist
Specialty Forensic Sciences
Date 2014 Mar 12
PMID 24611212
Citations 23
Affiliations
Soon will be listed here.
Abstract

The Deputy Administrator of the Drug Enforcement Administration (DEA) is issuing this final order to temporarily schedule 10 synthetic cathinones into schedule I pursuant to the temporary scheduling provisions of the Controlled Substances Act (CSA). The 10 substances are: 4-methyl-N-ethylcathinone (``4-MEC''); 4-methyl-alpha-pyrrolidinopropiophenone (``4-MePPP''); alpha-pyrrolidinopentiophenone (``[alpha]-PVP''); 1-(1,3-benzodioxol-5-yl)-2-(methylamino)butan-1-one (``butylone''); 2-(methylamino)-1-phenylpentan-1-one (``pentedrone''); 1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one (``pentylone''); 4-fluoro-N-methylcathinone (``4-FMC''); 3-fluoro-N-methylcathinone (``3-FMC''); 1-(naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one (``naphyrone''); and alpha-pyrrolidinobutiophenone (``[alpha]-PBP''). This action is based on a finding by the Deputy Administrator that the placement of these synthetic cathinones and their optical, positional, and geometric isomers, salts and salts of isomers into schedule I of the CSA is necessary to avoid an imminent hazard to the public safety. As a result of this order, the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances will be imposed on persons who handle (manufacture, distribute, import, export, engage in research, conduct instructional activities, and possess), or propose to handle these synthetic cathinones.

Citing Articles

Effects of Serial Polydrug Use on the Rewarding and Aversive Effects of the Novel Synthetic Cathinone Eutylone.

Manke H, Nunn S, Sulima A, Rice K, Riley A Brain Sci. 2023; 13(9).

PMID: 37759895 PMC: 10526358. DOI: 10.3390/brainsci13091294.


Effects of α-pyrrolidino-phenone cathinone stimulants on locomotor behavior in female rats.

Taffe M, Nguyen J, Vandewater S, Grant Y, Dickerson T Drug Alcohol Depend. 2021; 227:108910.

PMID: 34332176 PMC: 9812683. DOI: 10.1016/j.drugalcdep.2021.108910.


Flakka: New Dangerous Synthetic Cathinone on the Drug Scene.

Patocka J, Zhao B, Wu W, Klimova B, Valis M, Nepovimova E Int J Mol Sci. 2020; 21(21).

PMID: 33142953 PMC: 7663692. DOI: 10.3390/ijms21218185.


Stereoselective neurochemical, behavioral, and cardiovascular effects of α-pyrrolidinovalerophenone enantiomers in male rats.

Schindler C, Thorndike E, Walters H, Walther D, Rice K, Baumann M Addict Biol. 2019; 25(6):e12842.

PMID: 31724254 PMC: 7217742. DOI: 10.1111/adb.12842.


Emerging threats in addiction: will novel psychoactive substances contribute to exacerbating the ongoing drug overdose epidemic?.

Hall F, Miczek K Psychopharmacology (Berl). 2019; 236(3):839-843.

PMID: 31119328 DOI: 10.1007/s00213-019-05271-7.