Gaining Translational Momentum: More Zebrafish Models for Neuroscience Research

Overview

Journal Prog Neuropsychopharmacol Biol Psychiatry

Specialty Psychiatry

Date 2014 Mar 6

PMID 24593944

Citations 56

Authors

Allan V Kalueff

David J Echevarria

Adam Michael Stewart

Affiliations

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Abstract

Zebrafish (Danio rerio) are rapidly becoming a popular model organism in translational neuroscience and biological psychiatry research. Here we discuss conceptual, practical and other related aspects of using zebrafish in this field ("from tank to bedside"), and critically evaluate both advantages and limitations of zebrafish models of human brain disorders. We emphasize the need to more actively develop zebrafish models for neuroscience research focusing on complex traits.

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