Advanced Stage Micropapillary Serous Borderline Ovarian Tumor in a Postmenopausal Woman: a Case Report

Overview

Journal J Turk Ger Gynecol Assoc

Publisher Galenos Publishing House

Specialty Gynecology & Obstetrics

Date 2014 Mar 5

PMID 24592040

Authors

Tayfun Gungor

Metin Kaba

Eralp Baser

Hakan Yalcin

Hatice Bayramoglu

Mustafa Besli

Affiliations

Soon will be listed here.

Abstract

Serous borderline ovarian tumors (SBOT) generally occur in young women, present at early stages and are associated with an excellent prognosis. However, there are rare subtypes of SBOT which may exhibit a more aggressive course. In contrast with other types of SBOT, the micropapillary variant SBOT (SBOT-MP) tends to present at advanced stages. Herein, we present a rare case of a SBOT-MP that occurred in a 66-year-old woman, who had tumoral involvement on bilateral ovaries, sigmoid serosa and a positive peritoneal cytology. The currently recommended treatment options for these cases are also discussed.

References

Kanat-Pektas M, Ozat M, Gungor T, Sahin I, Yalcin H, Ozdal B . Complete lymph node dissection: is it essential for the treatment of borderline epithelial ovarian tumors?. Arch Gynecol Obstet. 2010; 283(4):879-84. DOI: 10.1007/s00404-010-1539-5. View

De Iaco P, Ferrero A, Rosati F, Melpignano M, Biglia N, Rolla M . Behaviour of ovarian tumors of low malignant potential treated with conservative surgery. Eur J Surg Oncol. 2008; 35(6):643-8. DOI: 10.1016/j.ejso.2008.09.011. View

Hogg R, Scurry J, Kim S, Friedlander M, Hacker N . Microinvasion links ovarian serous borderline tumor and grade 1 invasive carcinoma. Gynecol Oncol. 2007; 106(1):44-51. DOI: 10.1016/j.ygyno.2007.01.054. View

Laurent I, Uzan C, Gouy S, Pautier P, Duvillard P, Morice P . Results after conservative treatment of serous borderline tumors of the ovary with a micropapillary pattern. Ann Surg Oncol. 2008; 15(12):3561-6. DOI: 10.1245/s10434-008-0159-9. View

Woo M, Salamanca C, Miller M, Symowicz J, Leung P, Oliveira C . Serous borderline ovarian tumors in long-term culture: phenotypic and genotypic distinction from invasive ovarian carcinomas. Int J Gynecol Cancer. 2008; 18(6):1234-47. DOI: 10.1111/j.1525-1438.2007.01171.x. View

Longacre T, McKenney J, Tazelaar H, Kempson R, Hendrickson M . Ovarian serous tumors of low malignant potential (borderline tumors): outcome-based study of 276 patients with long-term (> or =5-year) follow-up. Am J Surg Pathol. 2005; 29(6):707-23. DOI: 10.1097/01.pas.0000164030.82810.db. View

Kacar Ozkara S . Significance of peritoneal washing cytopathology in ovarian carcinomas and tumors of low malignant potential: a quality control study with literature review. Acta Cytol. 2010; 55(1):57-68. DOI: 10.1159/000320858. View

Chang S, Ryu H, Chang K, Yoo S, Yoon J . Prognostic significance of the micropapillary pattern in patients with serous borderline ovarian tumors. Acta Obstet Gynecol Scand. 2008; 87(4):476-81. DOI: 10.1080/00016340801995640. View

Zanetta G, Rota S, Chiari S, Bonazzi C, BRATINA G, Mangioni C . Behavior of borderline tumors with particular interest to persistence, recurrence, and progression to invasive carcinoma: a prospective study. J Clin Oncol. 2001; 19(10):2658-64. DOI: 10.1200/JCO.2001.19.10.2658. View

10.

Yemelyanova A, Mao T, Nakayama N, Shih I, Kurman R . Low-grade serous carcinoma of the ovary displaying a macropapillary pattern of invasion. Am J Surg Pathol. 2008; 32(12):1800-6. PMC: 2706134. DOI: 10.1097/PAS.0b013e318181a7ce. View

11.

Kanat-Pektas M, Ozat M, Gungor T, Dikici T, Yilmaz B, Mollamahmutoglu L . Fertility outcome after conservative surgery for borderline ovarian tumors: a single center experience. Arch Gynecol Obstet. 2010; 284(5):1253-8. DOI: 10.1007/s00404-010-1804-7. View

12.

Winter 3rd W, Kucera P, Rodgers W, McBroom J, Olsen C, Maxwell G . Surgical staging in patients with ovarian tumors of low malignant potential. Obstet Gynecol. 2002; 100(4):671-6. DOI: 10.1016/s0029-7844(02)02171-3. View