American Society of Nephrology Quiz and Questionnaire 2013: Glomerulonephritis

Overview

Journal Clin J Am Soc Nephrol

Specialty Nephrology

Date 2014 Mar 1

PMID 24578330

Authors

Fernando C Fervenza

Mark A Perazella

Michael J Choi

Affiliations

Soon will be listed here.

Abstract

The Nephrology Quiz and Questionnaire (NQ&Q) remains an extremely popular session for attendees of the Annual Meeting of the American Society of Nephrology. As in past years, the conference hall of the 2013 meeting was overflowing with interested audience members. Topics covered by expert discussants included electrolyte and acid-base disorders, glomerular disease, ESRD/dialysis, and transplantation. Complex cases representing each of these categories, along with single best answer questions, were prepared by a panel of experts. Before the meeting, program directors of United States nephrology training programs answered questions through an Internet-based questionnaire. A new addition to the NQ&Q was participation in the questionnaire by nephrology fellows. To review the process, members of the audience test their knowledge and judgment on a series of case-oriented questions prepared and discussed by experts. Their answers are compared in real time using audience response devices with the answers of nephrology fellows and training program directors. The correct and incorrect answers are then briefly discussed after the audience responses and the results of the questionnaire are displayed. This article recapitulates the session and reproduces its educational value for CJASN readers. Enjoy the clinical cases and expert discussions.

References

Kyrieleis H, Lowik M, Pronk I, Cruysberg H, Kremer J, Oyen W . Long-term outcome of biopsy-proven, frequently relapsing minimal-change nephrotic syndrome in children. Clin J Am Soc Nephrol. 2009; 4(10):1593-600. PMC: 2758253. DOI: 10.2215/CJN.05691108. View

Faurschou M, Sorensen I, Mellemkjaer L, Loft A, Svalgaard Thomsen B, Tvede N . Malignancies in Wegener's granulomatosis: incidence and relation to cyclophosphamide therapy in a cohort of 293 patients. J Rheumatol. 2007; 35(1):100-5. View

Westhoff T, Schmidt S, Zidek W, Beige J, van der Giet M . Tacrolimus in steroid-resistant and steroid-dependent nephrotic syndrome. Clin Nephrol. 2006; 65(6):393-400. DOI: 10.5414/cnp65393. View

Fujinaga S, Hirano D, Murakami H, Ohtomo Y, Shimizu T, Kaneko K . Nephrotoxicity of once-daily cyclosporine A in minimal change nephrotic syndrome. Pediatr Nephrol. 2011; 27(4):671-4. DOI: 10.1007/s00467-011-2076-6. View

Ponticelli C, Edefonti A, Ghio L, Rizzoni G, Rinaldi S, GUSMANO R . Cyclosporin versus cyclophosphamide for patients with steroid-dependent and frequently relapsing idiopathic nephrotic syndrome: a multicentre randomized controlled trial. Nephrol Dial Transplant. 1993; 8(12):1326-32. View

Ishimoto T, Shimada M, Araya C, Huskey J, Garin E, Johnson R . Minimal change disease: a CD80 podocytopathy?. Semin Nephrol. 2011; 31(4):320-5. DOI: 10.1016/j.semnephrol.2011.06.002. View

Tsutsumi Y, Kanamori H, Mori A, Tanaka J, Asaka M, Imamura M . Reactivation of hepatitis B virus with rituximab. Expert Opin Drug Saf. 2005; 4(3):599-608. DOI: 10.1517/14740338.4.3.599. View

Pendse S, Ginsburg E, Singh A . Strategies for preservation of ovarian and testicular function after immunosuppression. Am J Kidney Dis. 2004; 43(5):772-81. DOI: 10.1053/j.ajkd.2004.01.008. View

Sellier-Leclerc A, Baudouin V, Kwon T, Macher M, Guerin V, Lapillonne H . Rituximab in steroid-dependent idiopathic nephrotic syndrome in childhood--follow-up after CD19 recovery. Nephrol Dial Transplant. 2011; 27(3):1083-9. DOI: 10.1093/ndt/gfr405. View

10.

Karras A, de Montpreville V, Fakhouri F, Grunfeld J, Lesavre P . Renal and thymic pathology in thymoma-associated nephropathy: report of 21 cases and review of the literature. Nephrol Dial Transplant. 2005; 20(6):1075-82. DOI: 10.1093/ndt/gfh615. View

11.

Guigonis V, Dallocchio A, Baudouin V, Dehennault M, Hachon-LE Camus C, Afanetti M . Rituximab treatment for severe steroid- or cyclosporine-dependent nephrotic syndrome: a multicentric series of 22 cases. Pediatr Nephrol. 2008; 23(8):1269-79. DOI: 10.1007/s00467-008-0814-1. View

12.

Francois H, Daugas E, Bensman A, Ronco P . Unexpected efficacy of rituximab in multirelapsing minimal change nephrotic syndrome in the adult: first case report and pathophysiological considerations. Am J Kidney Dis. 2006; 49(1):158-61. DOI: 10.1053/j.ajkd.2006.10.015. View

13.

Sawara Y, Itabashi M, Kojima C, Tabata H, Kamei D, Kawanishi K . Successful therapeutic use of a single-dose of rituximab on relapse in adults with minimal change nephrotic syndrome. Clin Nephrol. 2009; 72(1):69-72. DOI: 10.5414/cnp72069. View

14.

Kemper M, Meyer-Jark T, Lilova M, Muller-Wiefel D . Combined T- and B-cell activation in childhood steroid-sensitive nephrotic syndrome. Clin Nephrol. 2003; 60(4):242-7. DOI: 10.5414/cnp60242. View

15.

Haas M, Meehan S, Karrison T, SPARGO B . Changing etiologies of unexplained adult nephrotic syndrome: a comparison of renal biopsy findings from 1976-1979 and 1995-1997. Am J Kidney Dis. 1997; 30(5):621-31. DOI: 10.1016/s0272-6386(97)90485-6. View

16.

Praga M, Morales E, Herrero J, Perez Campos A, Dominguez-Gil B, Alegre R . Absence of hypoalbuminemia despite massive proteinuria in focal segmental glomerulosclerosis secondary to hyperfiltration. Am J Kidney Dis. 1999; 33(1):52-8. DOI: 10.1016/s0272-6386(99)70257-x. View

17.

Fujinaga S, Hirano D, Nishizaki N, Kamei K, Ito S, Ohtomo Y . Single infusion of rituximab for persistent steroid-dependent minimal-change nephrotic syndrome after long-term cyclosporine. Pediatr Nephrol. 2010; 25(3):539-44. DOI: 10.1007/s00467-009-1377-5. View

18.

Yang T, Nast C, Vo A, Jordan S . Rapid remission of steroid and mycophenolate mofetil (mmf)-resistant minimal change nephrotic syndrome after rituximab therapy. Nephrol Dial Transplant. 2007; 23(1):377-80. DOI: 10.1093/ndt/gfm592. View

19.

Nolasco F, Cameron J, Heywood E, Hicks J, Ogg C, Williams D . Adult-onset minimal change nephrotic syndrome: a long-term follow-up. Kidney Int. 1986; 29(6):1215-23. DOI: 10.1038/ki.1986.130. View

20.

Waldman M, John Crew R, Valeri A, Busch J, Stokes B, Markowitz G . Adult minimal-change disease: clinical characteristics, treatment, and outcomes. Clin J Am Soc Nephrol. 2007; 2(3):445-53. DOI: 10.2215/CJN.03531006. View