Nanopore Film Based Enrichment and Quantification of Low Abundance Hepcidin from Human Bodily Fluids

Overview

Journal Nanomedicine

Publisher Elsevier

Specialties Biomedical Engineering
Biotechnology

Date 2014 Feb 26

PMID 24566273

Citations 3

Authors

Jia Fan

Shiwen Niu

Ailian Dong

Jian Shi

Hung-Jen Wu

Daniel H Fine

Yaping Tian

Chunxi Zhou

Xuewu Liu

Tong Sun

Gregory J Anderson

Mauro Ferrari

Guangjun Nie

Ye Hu

Yuliang Zhao

Affiliations

Soon will be listed here.

Abstract

From The Clinical Editor: Diagnosing diseases with low concentration peptide biomarkers remains challenging. This team of authors describes a peptide extraction approach based on nanoporous silica thin films to successfully detect low concentrations of hepcidin from human body fluids collected from 119 healthy volunteers and 19 inflammation patients.

Citing Articles

Strategies for Characterization of Low-Abundant Intact or Truncated Low-Molecular-Weight Proteins From Human Plasma.

Cai T, Yang F Enzymes. 2017; 42:105-123.

PMID: 29054267 PMC: 7102702. DOI: 10.1016/bs.enz.2017.08.004.

Correlation of serum hepcidin levels with disease progression in hepatitis B virus-related disease assessed by nanopore film based assay.

Wang J, Dong A, Liu G, Anderson G, Hu T, Shi J Sci Rep. 2016; 6:34252.

PMID: 27694815 PMC: 5046114. DOI: 10.1038/srep34252.

Profiling of Cross-Functional Peptidases Regulated Circulating Peptides in BRCA1 Mutant Breast Cancer.

Fan J, Tea M, Yang C, Ma L, Meng Q, Hu T J Proteome Res. 2016; 15(5):1534-45.

PMID: 27058005 PMC: 5124559. DOI: 10.1021/acs.jproteome.6b00010.

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