The Impact of Peer Support and Mp3 Messaging on Adherence to Inhaled Corticosteroids in Minority Adolescents with Asthma: a Randomized, Controlled Trial

Overview

Journal J Allergy Clin Immunol Pract

Specialty Allergy & Immunology

Date 2014 Feb 26

PMID 24565620

Citations 20

Authors

Giselle Mosnaim

Hong Li

Molly Martin

DeJuran Richardson

Paula Jo Belice

Elizabeth Avery

Norman Ryan

Bruce Bender

Lynda Powell

Affiliations

Soon will be listed here.

Abstract

Background: Poor adherence to inhaled corticosteroids (ICS) is a critical risk factor contributing to asthma morbidity among low-income minority adolescents.

Objective: This trial tested whether peer support group meetings and peer asthma messages delivered via mp3 players improved adherence to ICS.

Methods: Low-income African American and/or Hispanic adolescents, ages 11-16 years old, with persistent asthma, and poor (≤ 48%) adherence to prescription ICS during the 3-week run-in were randomized to intervention or attention control groups (ATG) for the 10-week treatment. During treatment, the intervention arm subjects participated in weekly coping peer group support sessions and received mp3 peer-recorded asthma messages that promoted adherence. The ATG participated in weekly meetings with a research assistant and received an equivalent number of mp3 physician-recorded asthma messages. Adherence was measured by using self-report and the Doser CT, an electronic dose counter. The primary outcome was the difference in adherence at 10 weeks between the 2 arms.

Results: Thirty-four subjects were randomized to each arm. At 10 weeks, no statistical difference in objectively measured adherence could be detected between the 2 arms when adjusting for baseline adherence (P = .929). Adherence declined in both groups over the course of the active treatment period. In both study arms, self-reported adherence by participants was significantly higher than their objectively measured adherence at week 10 (P < .0001).

Conclusion: Improving medication adherence in longitudinal studies is challenging. Peer support and mp3-delivered peer asthma messages may not be of sufficient dose to improve outcomes.

Citing Articles

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References

Moorman J, Anne Rudd R, Johnson C, King M, Minor P, Bailey C . National surveillance for asthma--United States, 1980-2004. MMWR Surveill Summ. 2007; 56(8):1-54. View

Otsuki M, Eakin M, Rand C, Butz A, Hsu V, Zuckerman I . Adherence feedback to improve asthma outcomes among inner-city children: a randomized trial. Pediatrics. 2009; 124(6):1513-21. PMC: 5450495. DOI: 10.1542/peds.2008-2961. View

Logan D, Zelikovsky N, Labay L, Spergel J . The Illness Management Survey: identifying adolescents' perceptions of barriers to adherence. J Pediatr Psychol. 2003; 28(6):383-92. DOI: 10.1093/jpepsy/jsg028. View

Nelson H, Busse W, Kerwin E, Church N, Emmett A, Rickard K . Fluticasone propionate/salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast. J Allergy Clin Immunol. 2000; 106(6):1088-95. DOI: 10.1067/mai.2000.110920. View

Shah S, Peat J, Mazurski E, Wang H, Sindhusake D, Bruce C . Effect of peer led programme for asthma education in adolescents: cluster randomised controlled trial. BMJ. 2001; 322(7286):583-5. PMC: 26550. DOI: 10.1136/bmj.322.7286.583. View

Moorman J, Zahran H, Truman B, Molla M . Current asthma prevalence - United States, 2006-2008. MMWR Suppl. 2011; 60(1):84-6. View

Davis S, Krishnan J, Lee K, Persky V, Naureckas E . Effect of a community-wide asthma intervention on appropriate use of inhaled corticosteroids. J Urban Health. 2011; 88 Suppl 1:144-55. PMC: 3042072. DOI: 10.1007/s11524-010-9476-y. View

Martin M, Olson D, Mosnaim G, Ortega D, Rothschild S . Recruitment, asthma characteristics, and medication behaviors in Midwestern Puerto Rican youth: data from Project CURA. Ann Allergy Asthma Immunol. 2012; 109(2):121-7. PMC: 3408713. DOI: 10.1016/j.anai.2012.06.005. View

Williams L, Pladevall M, Xi H, Peterson E, Joseph C, Lafata J . Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma. J Allergy Clin Immunol. 2004; 114(6):1288-93. DOI: 10.1016/j.jaci.2004.09.028. View

10.

Agertoft L, Pedersen S . Effects of long-term treatment with an inhaled corticosteroid on growth and pulmonary function in asthmatic children. Respir Med. 1994; 88(5):373-81. DOI: 10.1016/0954-6111(94)90044-2. View

11.

Bandura A . Self-efficacy: toward a unifying theory of behavioral change. Psychol Rev. 1977; 84(2):191-215. DOI: 10.1037//0033-295x.84.2.191. View

12.

Lemanek K . Adherence issues in the medical management of asthma. J Pediatr Psychol. 1990; 15(4):437-58. DOI: 10.1093/jpepsy/15.4.437. View

13.

van Es S, Nagelkerke A, Colland V, Scholten R, Bouter L . An intervention programme using the ASE-model aimed at enhancing adherence in adolescents with asthma. Patient Educ Couns. 2001; 44(3):193-203. DOI: 10.1016/s0738-3991(00)00195-6. View

14.

Apter A, Reisine S, Affleck G, Barrows E, ZuWallack R . Adherence with twice-daily dosing of inhaled steroids. Socioeconomic and health-belief differences. Am J Respir Crit Care Med. 1998; 157(6 Pt 1):1810-7. DOI: 10.1164/ajrccm.157.6.9712007. View

15.

Milgrom H, Bender B, Ackerson L, Bowry P, Smith B, Rand C . Noncompliance and treatment failure in children with asthma. J Allergy Clin Immunol. 1996; 98(6 Pt 1):1051-7. DOI: 10.1016/s0091-6749(96)80190-4. View

16.

Bender B, Zhang L . Negative affect, medication adherence, and asthma control in children. J Allergy Clin Immunol. 2008; 122(3):490-5. DOI: 10.1016/j.jaci.2008.05.041. View

17.

Ryan D, Price D, Musgrave S, Malhotra S, Lee A, Ayansina D . Clinical and cost effectiveness of mobile phone supported self monitoring of asthma: multicentre randomised controlled trial. BMJ. 2012; 344:e1756. PMC: 3311462. DOI: 10.1136/bmj.e1756. View

18.

Krishnan J, Riekert K, McCoy J, Stewart D, Schmidt S, Chanmugam A . Corticosteroid use after hospital discharge among high-risk adults with asthma. Am J Respir Crit Care Med. 2004; 170(12):1281-5. DOI: 10.1164/rccm.200403-409OC. View

19.

Onyirimba F, Apter A, Reisine S, Litt M, McCusker C, Connors M . Direct clinician-to-patient feedback discussion of inhaled steroid use: its effect on adherence. Ann Allergy Asthma Immunol. 2003; 90(4):411-5. DOI: 10.1016/S1081-1206(10)61825-X. View

20.

Mosnaim G, Li H, Damitz M, Sharp L, Li Z, Talati A . Evaluation of the Fight Asthma Now (FAN) program to improve asthma knowledge in urban youth and teenagers. Ann Allergy Asthma Immunol. 2011; 107(4):310-6. DOI: 10.1016/j.anai.2011.07.008. View