Imaging Guidelines and Findings of Extracranial Glioblastoma

Overview

Journal J Neurooncol

Publisher Springer

Date 2014 Feb 22

PMID 24557958

Citations 9

Authors

Daniel Thomas Ginat

Pamela W Schaefer

Affiliations

Soon will be listed here.

Abstract

Extracranial manifestations of glioblastoma are uncommon and include a wide spectrum of entities, such as primary spinal cord glioblastoma, spinal leptomeningeal metastasis, seeding into the scalp following intracranial glioblastoma resection, direct extension of an intracranial glioblastoma though a craniotomy defect, dissemination via shunt catheter, and systemic metastasis, including lymphatic and hematogenous spread. Imaging plays an important role in the management of patients with extracranial glioblastomas and guidelines for the imaging evaluation of these lesions are reviewed. For example, MRI is the modality of choice for evaluating glioblastoma involving the scalp and spine. In particular, advanced imaging techniques such as MR spectroscopy, MR perfusion, diffusion-weighted imaging, and diffusion-tensor imaging can be useful for early detection and characterization of these lesions. CT and (18)FDG-PET are suitable modalities for evaluating systemic and CSF shunt-related metastases.

Citing Articles

Glioblastoma mimicking autoimmune meningitis in an adult: A complex diagnostic challenge.

Wakabayashi M, Ogiwara T, Ito K, Sato A, Hanaoka Y, Kobayashi K Surg Neurol Int. 2025; 16:61.

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Clinical Reasoning: A 63-Year-Old Man With Progressive Multicranial Neuropathy and Leptomeningeal Enhancement.

Taga A, Romo C, Rajan S, Lin D, Tobin G, Venkatesan A Neurology. 2024; 103(12):e210100.

PMID: 39586052 PMC: 11590232. DOI: 10.1212/WNL.0000000000210100.

Leptomeningeal Dissemination Complicated With Acute Tetraplegia From a Supratentorial Multicentric Isocitrate Dehydrogenase (IDH)-Wildtype Glioblastoma: A Case Report.

Visarion D, Cale I, Miron I, David B, Petrescu G, Pruna V Cureus. 2024; 16(3):e55777.

PMID: 38586710 PMC: 10999058. DOI: 10.7759/cureus.55777.

Intradural Intramedullary Spinal Cord Glioblastoma: A Case Report.

Shrestha P, Eineichner T, Wilson B, Lam N Cureus. 2023; 15(8):e43580.

PMID: 37593069 PMC: 10430890. DOI: 10.7759/cureus.43580.

Natural history of spinal cord metastasis from brain glioblastomas.

Amelot A, Terrier L, Cognacq G, Jecko V, Marlier B, Seizeur R J Neurooncol. 2023; 162(2):373-382.

PMID: 36991306 DOI: 10.1007/s11060-023-04298-3.

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