Minimally Invasive Surgery for Intracerebral Haemorrhage

Overview

Journal Curr Opin Crit Care

Specialty Critical Care

Date 2014 Feb 21

PMID 24553341

Citations 17

Authors

Benjamin Barnes

Daniel F Hanley

Juan R Carhuapoma

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: Spontaneous intracerebral haemorrhage (ICH) imposes a significant health and economic burden on society. Despite this, ICH remains the only stroke subtype without a definitive treatment. Without a clearly identified and effective treatment for spontaneous ICH, clinical practice varies greatly from aggressive surgery to supportive care alone. This review will discuss the current modalities of treatments for ICH including preliminary experience and investigative efforts to advance the care of these patients.

Recent Findings: Open surgery (craniotomy), prothrombotic agents and other therapeutic interventions have failed to significantly improve the outcome of these stroke victims. Recently, the Surgical Trial in Intracerebral Haemorrhage (STICH) II assessed the surgical management of patients with superficial intraparenchymal haematomas with negative results. MISTIE II and other trials of minimally invasive surgery (MIS) have shown promise for improving patient outcomes and a phase III trial started in late 2013.

Summary: ICH lacks a definitive primary treatment as well as a therapy targeting surrounding perihematomal oedema and associated secondary damage. An ongoing phase III trial using MIS techniques shows promise for providing treatment for these patients.

Citing Articles

Influx of Metabolites into Cerebrospinal Fluid in Intracerebral Hemorrhage is Associated with Increased Central Inflammation: a Retrospective Observational Study.

Zhang H, Zhong Y, Shao J, Sun K, Zhang L, Zhang Y Transl Stroke Res. 2025; .

PMID: 40069432 DOI: 10.1007/s12975-025-01342-4.

Minimally Invasive Surgery With Thrombolysis for Intracerebral Hemorrhage Evacuation: Bayesian Reanalysis of a Randomized Controlled Trial.

Bako A, Potter T, Pan A, Tannous J, Britz G, Ziai W Neurology. 2023; 101(16):e1614-e1622.

PMID: 37684058 PMC: 10585679. DOI: 10.1212/WNL.0000000000207735.

Laser navigation combined with XperCT technology-assisted puncture of basal ganglia intracerebral hemorrhage.

Yuan Z, Wei Q, Chen Z, Xing H, Zhang T, Li Z Neurosurg Rev. 2023; 46(1):104.

PMID: 37145343 DOI: 10.1007/s10143-023-02015-2.

New approach of minimally invasive evacuation for spontaneous supratentorial intracerebral hemorrhage.

Cai Q, Wang W, Li Z, Song P, Zhou L, Cheng L Am J Transl Res. 2022; 14(3):1969-1978.

PMID: 35422949 PMC: 8991136.

Minimally Invasive Surgery for Intracerebral and Intraventricular Hemorrhage.

Zheng Z, Wang Q, Sun S, Luo J Front Neurol. 2022; 13:755501.

PMID: 35273553 PMC: 8901716. DOI: 10.3389/fneur.2022.755501.

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