Pre- and Postovulatory Auditory Brainstem Response in Normal Women

Overview

Journal Indian J Otolaryngol Head Neck Surg

Publisher Springer

Date 2014 Feb 18

PMID 24533372

Citations 7

Authors

Namrata Upadhayay

Bishnu Hari Paudel

Paras Nath Singh

Bal Krishna Bhattarai

Kopila Agrawal

Affiliations

Soon will be listed here.

Abstract

Studies with ovarian hormones on auditory brainstem response (ABR) have conflicting reports although women have ABR shorter than men. This study compared ABR between pre- and postovulatory phases of menstrual cycle in consenting 40 healthy female volunteers (age 19 ± 2.35 years). The study was conducted under standard laboratory conditions (room temperature 26 ± 2°C) using Neuropack (Nihon Kohden machine, NM-420S; H636, Japan) and earphone dynamic receiver ELEGA (Type DR-531; no.237, Japan) in sound proof room. Ears were stimulated simultaneously using standard protocol. ABR was recorded in pre- and postovulatory phases. Ovulation was estimated by measuring basal body temperature. The ABR wave latencies (WLs) I, II, III, IV, V and inter-peak latencies (IPLs) I-III, III-V, I-V were compared between the two phases of menstrual cycle using paired t test. The postovulatory phase had shorter WL V (5.71 ± 0.18 ms vs. 5.81 ± 0.19 ms, p < 0.01), IPL III-V (1.89 ± 0.16 ms vs. 1.94 ± 0.19 ms, p < 0.05), and I-V (3.88 ± 0.16 ms vs. 3.95 ± 0.18 ms, p < 0.05) than in preovulatory. Other WLs and IPLs showed decreasing trend in postovulatory phase. ABR is better in postovulatory phase as compared to preovulatory phase probably due to progesterone hormone which might be involved in modulating auditory hearing pathway at postovulatory phase.

Citing Articles

Sex differences and the effect of female sex hormones on auditory function: a systematic review.

Aloufi N, Heinrich A, Marshall K, Kluk K Front Hum Neurosci. 2023; 17:1077409.

PMID: 37151900 PMC: 10161575. DOI: 10.3389/fnhum.2023.1077409.

Effect of estrogen and progesterone on nerve conduction studies during ovarian cycle.

Ustaomer K, Sozay S, Sarifakioglu B Turk J Phys Med Rehabil. 2022; 67(4):502-508.

PMID: 35141490 PMC: 8790261. DOI: 10.5606/tftrd.2021.6628.

Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks.

McFadden D, Champlin C, Pho M, Pasanen E, Maloney M, Leshikar E PLoS One. 2021; 16(5):e0251363.

PMID: 33979393 PMC: 8115856. DOI: 10.1371/journal.pone.0251363.

Auditory function and dysfunction: estrogen makes a difference.

Delhez A, Lefebvre P, Pequeux C, Malgrange B, Delacroix L Cell Mol Life Sci. 2019; 77(4):619-635.

PMID: 31522250 PMC: 11105012. DOI: 10.1007/s00018-019-03295-y.

Central conduction time in auditory brainstem response and ear advantage in dichotic listening across menstrual cycle.

Hu X, Lau C PLoS One. 2017; 12(11):e0187672.

PMID: 29121103 PMC: 5679549. DOI: 10.1371/journal.pone.0187672.

References

Kaur P, Jodhka P, Underwood W, Bowles C, de Fiebre N, de Fiebre C . Progesterone increases brain-derived neuroptrophic factor expression and protects against glutamate toxicity in a mitogen-activated protein kinase- and phosphoinositide-3 kinase-dependent manner in cerebral cortical explants. J Neurosci Res. 2007; 85(11):2441-9. PMC: 2693123. DOI: 10.1002/jnr.21370. View

Wallace E, MALINAK L, Jerger J . Sex hormones regulate ABR latency. Otolaryngol Head Neck Surg. 1994; 110(1):46-52. DOI: 10.1177/019459989411000105. View

Garcia-Segura L, Azcoitia I, Doncarlos L . Neuroprotection by estradiol. Prog Neurobiol. 2000; 63(1):29-60. DOI: 10.1016/s0301-0082(00)00025-3. View

Henderson V, Paganini-Hill A, Miller B, Elble R, Reyes P, Shoupe D . Estrogen for Alzheimer's disease in women: randomized, double-blind, placebo-controlled trial. Neurology. 2000; 54(2):295-301. DOI: 10.1212/wnl.54.2.295. View

Caruso S, Maiolino L, Rugolo S, Intelisano G, Farina M, Cocuzza S . Auditory brainstem response in premenopausal women taking oral contraceptives. Hum Reprod. 2003; 18(1):85-9. DOI: 10.1093/humrep/deg003. View

Dehan C, Jerger J . Analysis of gender differences in the auditory brainstem response. Laryngoscope. 1990; 100(1):18-24. DOI: 10.1288/00005537-199001000-00005. View

Wallace E, Stach B, JERGER J . Cyclic steroid replacement alters auditory brainstem responses in young women with premature ovarian failure. Hear Res. 1992; 64(1):93-8. DOI: 10.1016/0378-5955(92)90171-i. View

Hultcrantz M, Simonoska R, Stenberg A . Estrogen and hearing: a summary of recent investigations. Acta Otolaryngol. 2005; 126(1):10-4. DOI: 10.1080/00016480510038617. View

Serra A, Maiolino L, Agnello C, Messina A, Caruso S . Auditory brain stem response throughout the menstrual cycle. Ann Otol Rhinol Laryngol. 2003; 112(6):549-53. DOI: 10.1177/000348940311200612. View

10.

Tasman A, Hahn T, Maiste A . Menstrual cycle synchronized changes in brain stem auditory evoked potentials and visual evoked potentials. Biol Psychiatry. 1999; 45(11):1516-9. DOI: 10.1016/s0006-3223(98)00196-6. View

11.

Khaliq F, Tandon O, Goel N . Differential effects of exogenous estrogen versus a estrogen-progesterone combination on auditory evoked potentials in menopausal women. Indian J Physiol Pharmacol. 2006; 49(3):345-52. View

12.

Caruso S, Maiolino L, Agnello C, Garozzo A, Di Mari L, Serra A . Effects of patch or gel estrogen therapies on auditory brainstem response in surgically postmenopausal women: a prospective, randomized study. Fertil Steril. 2003; 79(3):556-61. DOI: 10.1016/s0015-0282(02)04763-5. View

13.

Yadav A, Tandon O, Vaney N . Auditory evoked responses during different phases of menstrual cycle. Indian J Physiol Pharmacol. 2003; 46(4):449-56. View

14.

Nadal A, Diaz M, Valverde M . The estrogen trinity: membrane, cytosolic, and nuclear effects. News Physiol Sci. 2001; 16:251-5. DOI: 10.1152/physiologyonline.2001.16.6.251. View

15.

Wright D, Bauer M, Hoffman S, Stein D . Serum progesterone levels correlate with decreased cerebral edema after traumatic brain injury in male rats. J Neurotrauma. 2001; 18(9):901-9. DOI: 10.1089/089771501750451820. View

16.

Ben david Y, Tal J, Podoshin L, Fradis M, Sharf M, Pratt H . Brain stem auditory evoked potentials: effects of ovarian steroids correlated with increased incidence of Bell's palsy in pregnancy. Otolaryngol Head Neck Surg. 1995; 113(1):32-5. DOI: 10.1016/S0194-59989570141-9. View

17.

Ciriza I, Azcoitia I, Garcia-Segura L . Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivo. J Neuroendocrinol. 2004; 16(1):58-63. DOI: 10.1111/j.1365-2826.2004.01121.x. View

18.

Zani A . Brain evoked responses reflect information processing changes with the menstrual cycle in young female athletes. J Sports Med Phys Fitness. 1989; 29(1):113-21. View

19.

Kilicdag E, Yavuz H, Bagis T, Tarim E, Erkan A, Kazanci F . Effects of estrogen therapy on hearing in postmenopausal women. Am J Obstet Gynecol. 2004; 190(1):77-82. DOI: 10.1016/j.ajog.2003.06.001. View

20.

Yadav A, Tandon O, Vaney N . Long latency auditory evoked responses in ovulatory and anovulatory menstrual cycle. Indian J Physiol Pharmacol. 2004; 47(2):179-84. View