Diffusion Tensor Imaging for in Vivo Detection of Degenerated Optic Radiation

Overview

Journal ISRN Ophthalmol

Specialty Ophthalmology

Date 2014 Feb 18

PMID 24533184

Citations 1

Authors

Georg Michelson

Tobias Engelhorn

Simone Waerntges

Arnd Doerfler

Affiliations

Soon will be listed here.

Abstract

Glaucomatous optic nerve atrophy may continue to the linked optic radiation by transneuronal degeneration, as described in animal models of glaucoma. In vivo visualization of the visual pathway represents a new challenge in the field of ophthalmology. We present a new approach for illustration of the optic radiation by diffusion tensor imaging (DTI) based on magnetic resonance imaging (MRI). The DTI was established by use of a 3T high-field scanner. The case of a patient with primary open-angle glaucoma is opposed to this one of a healthy subject to demonstrate the visible rarefication of the optic radiation. The goal was to introduce the technique of the DTI also in ophthalmology and to demonstrate that it may be useful to judge glaucoma-related differences.

Citing Articles

Transneuronal Degeneration in the Brain During Glaucoma.

You M, Rong R, Zeng Z, Xia X, Ji D Front Aging Neurosci. 2021; 13:643685.

PMID: 33889083 PMC: 8055862. DOI: 10.3389/fnagi.2021.643685.

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