Primary Reperfusion in Acute Right Ventricular Infarction: An Observational Study

Overview

Journal World J Cardiol

Publisher Baishideng Publishing Group

Specialty Cardiology & Vascular Diseases

Date 2014 Feb 15

PMID 24527184

Citations 4

Authors

Eulo Lupi-Herrera

Hector Gonzalez-Pacheco

Ursulo Juarez-Herrera

Nilda Espinola-Zavaleta

Eduardo Chuquiure-Valenzuela

Ramon Villavicencio-Fernandez

Marco Antonio Pena-Duque

Ernesto Ban-Hayashi

Sergio Ferez-Santander

Affiliations

Soon will be listed here.

Abstract

Aim: To investigate the impact of primary reperfusion therapy (RT) on early and late mortality in acute right ventricular infarction (RVI).

Methods: RVI patients (n = 679) were prospectively classified as without right ventricular failure (RVF) (class A, n = 425, 64%), with RVF (class B, n = 158, 24%) or with cardiogenic shock (CS) (class C, n = 96, 12%). Of the 679 patients, 148 (21.7%) were considered to be eligible for thrombolytic therapy (TT) and 351 (51.6%) for primary percutaneous coronary intervention (PPCI). TIMI 3-flow by TT was achieved for A, B and C RVI class in 65%, 64% and 0%, respectively and with PPCI in 93%, 91% and 87%, respectively.

Results: For class A without RT, the mortality rate was 7.9%, with TT was reduced to 4.4% (P < 0.01) and with PPCI to 3.2% (P < 0.01). Considering TT vs PPCI, PPCI was superior (P < 0.05). For class B without RT the mortality was 27%, decreased to 13% with TT (P < 0.01) and to 8.3% with PPCI (P < 0.01). In a TT and PPCI comparison, PPCI was superior (P < 0.01). For class C without RT the in-hospital mortality was 80%, with TT was 100% and with PPCI, the rate decreased to 44% (P < 0.01). At 8 years, the mortality rate without RT for class A was 32%, for class B was 48% and for class C was 85%. When PPCI was successful, the long-term mortality was lower than previously reported for the 3 RVI classes (A: 21%, B: 38%, C: 70%; P < 0.001).

Conclusion: PPCI is superior to TT and reduces short/long-term mortality for all RVI categories. RVI CS patients should be encouraged to undergo PPCI at a specialized center.

Citing Articles

Impact of right ventricular failure on the outcomes of acute inferior wall myocardial infarction.

Shrivastav R, Malik A, Hajra A, Goel A, Mandal A, Mukhopadhyay S Future Cardiol. 2024; 20(10):563-569.

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Mechanism of heart failure after myocardial infarction.

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Heart Failure After Right Ventricular Myocardial Infarction.

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[Cardiogenic shock complicating myocardial infarction].

Werdan K, Ferrari M, Prondzinsky R, Russ M Herz. 2022; 47(1):85-100.

PMID: 35015088 DOI: 10.1007/s00059-021-05088-1.

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