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Photoredox-induced Three-component Oxy-, Amino-, and Carbotrifluoromethylation of Enecarbamates

Overview
Journal Org Lett
Specialties Biochemistry
Chemistry
Date 2014 Feb 14
PMID 24520865
Citations 19
Authors
Affiliations
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Abstract

A photoredox-catalzyed trifluoromethylation of enecarbamates process is reported. This pathway uses Togni's reagent as the CF3 source and follows a radical/cationic pathway. Under the optimized conditions using [Ru(bpy)3(PF6)2] as the photocatalyst, a wide range of substituted enecarbamates can readily be difunctionalized by means of various O, N, and C nucleophiles.

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